Bradycardia compositions
Abstract
Abstract BRADYCARDIA COMPOSITIONS HAVING N - ISOPROPYL-NORADRENALINE ANTAGONISTIC ACTIVITY AND METHOD OF INDUCING SAID ACTIVITY IN WARM-BLOODED ANIMALS USING AS THE ACTIVE INGREDIENT AT LEAST ONE 1-SUBSTITUTED PHENOXY-2-HYDROXY3-N-ISOPROPYLAMINO PROPANE OF THE FORMULA (R,R1,R2-PHENYL)-O-CH2-CH(-OH)-CH2-NH-CH(-CH3)2 WHEREIN R IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, HALOGEN, ALKYL OF 1 TO 4 CARBON ATOMS, ALKOXY OF 1 TO 4 CARBON ATOMS, HYDROXYALKYL OF 1 TO 4 CARBON ATOMS, HYDROXYCARBONYL, ALKOXYCARBONYL OF 1 TO 4 CARBON ATOMS, ALKENYL OF 2 TO 4 CARBON ATOMS, ALKYNYL OF 2 TO 4 CARBON ATOMS, ALKYLTHIO OF 1 TO 4 CARBON ATOMS AND CYANO, R1 IS -(CH2)X-NH2 WHERE X IS AN INTEGER FROM 0 TO 3 AND R2 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, HALOGEN, ALKYL OF 1 TO 4 CARBON ATOMS AND ALKOXY OF 1 TO 4 CARBON ATOMS, EITHER AS A RACEMATE OR AN OPTICALLY ACTIVE ISOMER, OR ITS NONTOXIC PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT.
Inventors
- 👤 G Ludwig
- 👤 K Zeile
- 👤 H Koppe
- 👤 A Engelhardt
Bibliographic Details
Claims Analysis
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