Patent US2989052A successfully refreshed from Google Patents.
US3734097A
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Therapeutic adhesive tape
Assignee: Alza Corp
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Filing: 1971-04-23
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Granted: 1973-05-22
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Expires: 1991-04-23
Abstract
Abstract Adhesive laminate tape for the topical administration of controlled therapeutically effective quantities of drug selected from the group consisting of anti-neoplastic agents, folic acid antagonists and anit-mitotic agents for the treatment of skin lesions, comprising a backing member bearing a pressure-sensitive adhesive, the adhesive having distributed therein a means for metering the flow of a therapeutically effective amount of the drug to the lesions over a prolonged period of time.
Inventors
- 👤 A Zaffaroni
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:36
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61F; A61F9/00; A61F9/0008; A61F9/0017; A61K9/7061; A61K9/7076; A61K9/7084; A61K9/7092; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/44; A61L15/58; A61M; A61M31/00; A61M31/002; A61L2300/00; A61L2300/40; A61L2300/41; A61L2300/416; A61L2300/432; A61L2300/60; A61L2300/602; A61L2300/62; A61L2300/622
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
30 words
The therapeutic adhesive tape of claim 1 wherein said microcapsules (3) comprise a matrix of the drug release rate controlling wall material, said matrix having the therapeutic agent distributed therethrough.
Claim 2
Dependent Claim
24 words
The therapeutic adhesive tape of claim 1 wherein said microcapsules (3) comprise the therapeutic agent microencapsulated within the drug release rate controlling wall material.
Claim 3
Dependent Claim
25 words
The therapeutic adhesive tape of claim 1 wherein said folic acid antagonist is selected from the group consisting of methotrexate, aminopterin, 3''-chloromethotrexate and 3'', 5''-dichloromethotrexate.
Claim 4
Dependent Claim
24 words
The therapeutic adhesive tape of claim 1 wherein said anti-neoplastic agent is selected from the group consisting of vincristine, vinblastine, 5-fluorouracil, 5-fluorodeoxyuridine and 6-mercotopurine.
Claim 5
Dependent Claim
33 words
The therapeutic adhesive tape of claim 1 wherein said therapeutic agent is methotrexate present at a concentration of 0.01 to 100 micrograms of methotrexate per sq. cm. of surface of pressure-sensitive adhesive coating.
Claim 6
Dependent Claim
12 words
The therapeutic adhesive tape of claim 1 further containing an anti-inflammatory steroid.
Claim 7
Dependent Claim
126 words
A therapeutic adhesive tape for the topical administration of controlled quantities of drug for the treatment of skin lesions, said tape comprising a laminate of (1) a backing member; (2) a discrete middle reservoir layer containing a therapeutic agent selected from the group consisting of an anti-neoplastic agent and a folic acid antagonist confined within a wall member, said wall member being formed from drug release rate controlling material to continuously meter the flow of a therapeutically effective amount of the therapeutic agent to the skin lesions from the reservoir at a controlled and predetermined rate over a period of time; and (3) a pressure-sensitive adhesive surface adapted for contact with the skin and positioned on one wall of the reservoir remote from the backing member.
Claim 8
Dependent Claim
24 words
The therapeutic adhesive tape of claim 8 where the reservoir layer (2) comprises a walled container having an interior chamber containing the therapeutic agent.
Claim 9
Dependent Claim
31 words
The therapeutic adhesive tape of claim 8 wherein the reservoir layer (2) comprises a matrix of the drug release rate controlling wall material, said matrix having the therapeutic agent distributed therethrough.
Claim 10
Dependent Claim
21 words
The therapeutic adhesive tape of claim 8 further including a solubility membrane interposed between said reservoir and said pressure-sensitive adhesive coating.
Claim 11
Dependent Claim
25 words
The therapeutic adhesive tape of claim 8 wherein said folic acid antagonist is selected from the group consisting of methotrexate, aminopterine, 3''-chloromethotrexate and 3'', 5''-dichloromethotrexate.
Claim 12
Dependent Claim
24 words
The pressure-sensitive adhesive tape of claim 8 wherein said anti-neoplastic agent is selected from the group consisting of vincristine, vinblastine, 5-fluorouracil, 5-fluorodexyuridine, and 6-mercoptopurine.
Claim 13
Dependent Claim
13 words
The therapeutic adhesive tape of claim 8 wherein said therapeutic agent is methotrexate.
Claim 14
Dependent Claim
33 words
The therapeutic adhesive tape of claim 8 wherein said therapeutic agent is methotrexate present at a concentration of 0.01 to 100 micrograms of methotrexate per sq. cm. of surface of pressure-sensitive adhesive coating.
Claim 15
Dependent Claim
12 words
The therapeutic adhesive tape of claim 8 further including an anti-inflammatory steroid.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-05-21 | 1976-11-20 | 1977-05-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-05-21 | 1980-11-20 | 1981-05-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-05-21 | 1984-11-20 | 1985-05-22 | $7700.00 | Window Closed / Lapsed |