N-(heteroarcyclic)piperazinylalkyl-azaspiroalkanediones
Abstract
Abstract THE PRESENT INVENTION CONCERNS THE CLASS OF HETEROCYCLIC CARBON COMPOUNDS COMPRISED OF N-(HETEROARCYCLIC)PIPERAZINYLALKYL DERIVATIVES OF AZASPIROALKANEDIONES WHICH HAVE POTENT AND SPECIFIC TRANQUILIZING ACTION AND ANTIEMETIC PROPERTIES. FURTHER, THIS INVENTION IS CONCERNED WITH THE SYNTHETIC PROCESS FOR THE PREPARATION OF N-(HETEROARCYCLIC)PIPERAZINYLALKYLAZASPIROALKANEDIONES WHICH COMPRISES REACTION OF SPIRO-SUBSTITUTED GLUTARIC ANHYDRIDE OR IMIDE WITH N(HETEROARCYCLIC)PIPERAZINE DERIVATIBES. TYPICAL EMBODIMENTS OF THIS INVENTION ARE 8-(4(4-(2-PYRIMIDINYL)-1-PIPERAZINYL)-BUTYL)-8-AZASPIRO(4.5) DECANE-7,9-DIONE AND 8-(4-(4-(2-PYRIDYL)-1-PIPERAZINYL)) BUTYL)-8-AZASPIRO(4,5) DECANE-7,9-DIONE.
Inventors
- 👤 Y Wu
- 👤 J Rayburn
Bibliographic Details
Claims Analysis
Total Claims: 0References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-02-20 | 1976-08-21 | 1977-02-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-02-20 | 1980-08-21 | 1981-02-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-02-20 | 1984-08-21 | 1985-02-20 | $7700.00 | Window Closed / Lapsed |