US3715372A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Derivatives of antibiotic x-537a
Assignee: F Hoffmann La Roche AG
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Filing: 1969-08-18
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Granted: 1973-02-06
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Expires: 1989-08-18
Abstract
Abstract where R1 is hydrogen, lower alkyl, phenyl, or phenyl substituted by halogen, nitro or lower alkyl; R2 is hydrogen; lower alkyl; lower alkanoyl; benzoyl; benzoyl substituted by halogen, nitro or lower alkyl; or R3 is hydrogen, halogen; nitro, amino, loweralkylamido or lower alkylamino; R4 is -OH, =O or =NOH which compound is useful as a coccidiostatic agent and as an anti-bacterial agent.
Inventors
- 👤 A Stempel
- 👤 J Westley
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 20:18
CPC Classifications
A; A23; A23K; A23K20/00; A23K20/10; A23K20/195
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
11 words
A compound selected from the group of compounds of the formula
Claim 2
Dependent Claim
11 words
A compound selected from the group of compounds of the formula
Claim 3
Dependent Claim
11 words
The compound of claim 1 which is 5-nitro-3-methyl-6-(7-ethyl-3,5-dimethyl-6-oxo-7-(5-ethyl-3-methyl-5-(5 -ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl)-2-tetrahydrofuryl)-4 -heptenyl)salicylic acid.
Claim 4
Dependent Claim
11 words
A compound selected from the group of compounds of the formula
Claim 5
Dependent Claim
11 words
A compound selected from the group of compounds of the formula
Claim 6
Dependent Claim
14 words
A compound of claim 3 wherein R2'' is lower alkanoyl and R3'' is hydrogen.
Claim 7
Dependent Claim
17 words
The compound of claim 4 (wherein R2'' is acetyl i.e.,) which is 3-methyl-6-(7-ethyl-4-hydroxy-3,5-dimethyl-6-oxo-7-(5-ethyl-3-methyl-5-(5 -ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl)-2 -tetrahydrofuryl)heptyl)acetyl salicylic acid.
Claim 8
Dependent Claim
15 words
The compound of claim 4 (wherein R2'' is propionyl i.e.,) which is 3-methyl-2-propionyloxy-6-(7-ethyl-4-hydroxy-3,5-dimethyl-6-oxo-7-(5-ethyl-3-methyl-5-(5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl)-2 -tetrahydrofuryl)heptyl)benzoic acid.
Claim 9
Dependent Claim
16 words
The compound of claim 4 (wherein R2'' is butyryl i.e.,) which is 2-butyryloxy-3-methyl-6-(7ethyl-4-hydroxy-3,5-dimethyl-6-oxo-7-(5-ethyl-3-5 -(5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl)-2 -tetrahydrofuryl)heptyl)benzoic acid
Claim 10
Dependent Claim
13 words
A compound of claim 3 wherein R2'' is hydrogen and R3'' is halogen.
Claim 11
Dependent Claim
10 words
The compound of claim 8 which is 5-bromo-3-methyl-6-(7-ethyl-4-hydroxy-3,5-dimethyl-6-oxo-7-(5-ethyl-3-methyl-5-(5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl)-2 -tetrahydrofuryl)heptyl)salicylic acid.
Claim 12
Dependent Claim
11 words
The compound of claim 8 which is 5-chloro-3-methyl-6-(7-ethyl-4-hydroxy-3,5-dimethyl-6-oxo-7-(5-ethyl-3 -methyl-5-(5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl)-2 -tetrahydrofuryl)heptyl)salicylic acid.
Claim 13
Dependent Claim
101 words
The compound of claim 8 which is 5-iodo-3-methyl-6-(7-ethyl-4-hydroxy-3,5-dimethyl-6-oxo-7-(5-ethyl-2-methyl -5-(5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl)-2 -tetrahydrofuryl)heptyl)salicylic acid. wherein R1 is selected from the group consisting of hydrogen, lower alkyl, phenyl, and phenyl substituted by a member of the group consisting of halogen, nitro and lower alkyl; R2 is selected from the group consisting of hydrogen, lower alkyl, lower alkanoyl, benzoyl, and benzoyl substituted by a member of the group consisting of halogen, nitro and lower alkyl; and R3 is selected from the group consisting of hydrogen, halogen, nitro, amino, lower alkylamido and lower alkylamino and the pharmaceutically acceptable alkali metal, alkaline earth metal and ammonium salts thereof.
References Cited (Backward Citations)
US3501568A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-02-06 | 1976-08-07 | 1977-02-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-02-06 | 1980-08-07 | 1981-02-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-02-06 | 1984-08-07 | 1985-02-06 | $7700.00 | Window Closed / Lapsed |