US3714229A
Expired / Lapsed
US
⏱️ 0.0 years remaining
ESTERS OF 3-HYDROXY- alpha -(1-AMINOETHYL)-BENZYL ALCOHOL
Assignee: Merck and Co Inc
•
Filing: 1969-07-10
•
Granted: 1973-01-30
•
Expires: 1989-07-10
Abstract
Abstract Novel derivatives of 3-hydroxy- Alpha -(1-aminoethyl)-benzyl alcohol, particularly ester derivatives of erythro or threo 3hydroxy- Alpha -(1-aminoethyl)-benzyl alcohol and the corresponding 3-ether and 3-ester derivatives thereof, are described. Processes for preparing such novel compounds are also described. The novel compounds are useful as antihypertensive agents and inhibitors of gastric secretion.
Inventors
- 👤 W Saari
- 👤 C Miller
- 👤 R Miller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 19:42
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/21; A61K31/215; A61K31/235; A61K31/24; A61P; A61P1/00; A61P1/04; A61P9/00; A61P9/12; C; C07; C07C; C07C45/00; C07C45/004; C07C49/00; C07C49/76; C07C49/84
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
14 words
A compound selected from the group consisting of (1) a compound of the formula
Claim 2
Dependent Claim
14 words
A compound selected from the group consisting of (1) a compound of the formula
Claim 3
Dependent Claim
13 words
A compound of claim 1 wherein R2 is hydrogen, phenyl or lower alkyl.
Claim 4
Dependent Claim
19 words
A compound of claim 1 wherein R2 is hydrogen, phenyl, or lower alkyl; R3, R1 and X are hydrogen.
Claim 5
Dependent Claim
9 words
A compound of claim 1 wherein X is hydrogen.
Claim 6
Dependent Claim
9 words
A compound of claim 1 in the erythro configuration.
Claim 7
Dependent Claim
14 words
A compound of claim 3 wherein the side chain is in the erythro configuration.
Claim 8
Dependent Claim
15 words
A compound of claim 3 wherein the side chain is in the erythro (1R,2S) configuration.
Claim 9
Dependent Claim
10 words
A compound of claim 1, being erythro Alpha -(1-aminoethyl)-3-hydroxybenzyl acetate.
Claim 10
Dependent Claim
10 words
A compound of claim 1, being erythro Alpha -(1-aminoethyl)-3-hydroxybenzyl benzoate.
Claim 11
Dependent Claim
10 words
A compound of claim 1, being erythro Alpha -(1-aminoethyl)-3-(m-chlorobenzyloxy)-benzyl acetate.
Claim 12
Dependent Claim
10 words
A compound of claim 1, being erythro Alpha -(1-aminoethyl)-3-(m-chlorobenzyloxy)-benzyl benzoate.
Claim 13
Dependent Claim
10 words
A compound of claim 1, being erythro Alpha -(1-aminoethyl)-3-methoxybenzyl acetate.
Claim 14
Dependent Claim
10 words
A compound of claim 1, being erythro Alpha -(1-aminoethyl)-3-methoxybenzyl benzoate.
Claim 15
Dependent Claim
10 words
A compound of claim 1, being erythro Alpha -(1-aminoethyl)-3-benzoyloxybenzyl benzoate.
References Cited (Backward Citations)
US2442797A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-01-30 | 1976-07-31 | 1977-01-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-01-30 | 1980-07-31 | 1981-01-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-01-30 | 1984-07-31 | 1985-01-30 | $7700.00 | Window Closed / Lapsed |