US3713980A
Expired / Lapsed
US
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Process for the preparation of peruvoside
Assignee: Merck Patent GmbH
•
Filing: 1970-11-24
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Granted: 1973-01-30
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Expires: 1990-11-24
Abstract
Abstract Peruvoside is obtained in high yield employing a greasy vegetable source of peruvoside, e.g., the fruit or seeds of Apocynacea Thevetia peruviana, for the fermentation step which releases glycosides from vegetable sources thereof. The glycosides are then extracted from the fermentation product and the peruvoside is separated from the extracted glycoside mixture by chromatography.
Inventors
- 👤 G Balsam
- 👤 O Kufner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 18:39
CPC Classifications
A; A61; A61K; A61K36/00; A61K36/18; A61K36/185; A61K36/24
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
53 words
In the commercial production of peruvoside by the fermentation of peruvoside-containing vegetable matter and the solvent extraction of the glycosides from the fermentation product and chromatographic separation of the peruvoside from the extracted glycosides, the improvement which comprises employing in the fermentation process a fatty vegetable source of the peruvoside in non-degreased form.
Claim 2
Dependent Claim
53 words
In the commercial production of peruvoside by the fermentation of peruvoside-containing vegetable matter and the solvent extraction of the glycosides from the fermentation product and chromatographic separation of the peruvoside from the extracted glycosides, the improvement which comprises employing in the fermentation process a fatty vegetable source of the peruvoside in non-degreased form.
Claim 3
Dependent Claim
25 words
A process according to claim 1 wherein the non-degreased fatty vegetable source of the peruvoside is the fruit or seeds of the plant Thevetia peruviana.
Claim 4
Dependent Claim
19 words
A process according to claim 1 wherein the glycosides are extracted from the fermentation product with methanol or acetone.
Claim 5
Dependent Claim
21 words
A process according to claim 1 wherein prior to chromatography the extracted glycosides are degreased with carbon tetrachloride or petroleum ether.
Claim 6
Dependent Claim
20 words
A process according to claim 4 wherein prior to degreasing the methanol or acetone solution of extracted glycosides is concentrated.
Claim 7
Dependent Claim
22 words
A process according to claim 4 wherein the glycosides in the degreased concentrated glycoside extract are extracted therefrom with dichloromethane or chloroform.
Claim 8
Dependent Claim
20 words
A process according to claim 6 wherein the glycosides are precipitated from the dichloromethane or chloroform solution with petroleum ether.
Claim 9
Dependent Claim
23 words
A process according to claim 6 wherein the dichloromethane or chloroform solution is concentrated and the glucosides then precipitated therefrom with petroleum ether.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-01-30 | 1976-07-31 | 1977-01-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-01-30 | 1980-07-31 | 1981-01-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-01-30 | 1984-07-31 | 1985-01-30 | $7700.00 | Window Closed / Lapsed |