US3711602A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Compositions for topical application for enhancing tissue penetration of physiologically active agents with dmso
Assignee: Gaylord Container Corp
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Filing: 1970-10-30
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Granted: 1973-01-16
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Expires: 1990-10-30
Abstract
Abstract Compositions for topical application for enhancing tissue penetration of physiologically active agents with dimethyl sulfoxide (DMSO). Such agents include physiologically active steroids, antineoplastic agents, antigens, antihistaminic agents, neuropharmacologic agents, antiinflammatory agents, anticoagulants, vasodilators, ultra-violet screening agents and nutrients. Such compositions, which may be in the form of lotions, ointments and suppositories, include the physiologically active agent, at least 10% by weight of DMSO and a pharmaceutically acceptable thickening agent. Liquid formulations for topical application of DMSO and the physiologically active agent in spray containers are also provided.
Inventors
- 👤 R Herschler
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 15:04
CPC Classifications
A; A61; A61K; A61K47/00; A61K47/06; A61K47/20; A61K9/00; A61K9/0012; A61K9/0014
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
24 words
A composition as in claim 1 for dermal application and wherein said DMSO comprises at least about 50 percent by weight of said composition.
Claim 2
Dependent Claim
31 words
A composition as in claim 2 and wherein said agent is selected from the group consisting of physiologically active steroids, antineoplastic agents, antigens, antihistaminic agents, analgesics, local anaesthetics and antiinflammatory agents.
Claim 3
Dependent Claim
17 words
A composition as in claim 1 and wherein said composition is in the form of a lotion.
Claim 4
Dependent Claim
17 words
A composition as in claim 1 and wherein said composition is in the form of an ointment.
Claim 5
Dependent Claim
17 words
A composition as in claim 1 and wherein said composition is in the form of a suppository.
Claim 6
Dependent Claim
99 words
A container provided with liquid spray dispensing means and containing a fluid, sprayable composition which comprises an amount of a physiologically active agent effective to produce the desired physiological effect on topical application of the composition to an external membrane of a human or animal, said agent being selected from the group consisting of physiologically active steroids, antineoplastic agents, antigens, antihistaminic agents, neuropharmacologic agents, antiinflammatory agents, anticoagulants, vasodilators, ultra-violet screening agents and nutrients, and an amount of DMSO effective to enhance external membrane penetration of said agent and comprising at least about 10 percent by weight of said composition.
Claim 7
Dependent Claim
26 words
A container as in claim 7 and wherein said DMSO in the composition charged therein comprises at least about 50 percent by weight of said composition.
Claim 8
Dependent Claim
18 words
A container as in claim 7 and wherein said container is an aerosol bomb containing a halocarbon propellant.
Claim 9
Dependent Claim
14 words
A container as in claim 7 and wherein said container is a squeeze bottle.
Claim 10
Dependent Claim
20 words
A container as in claim 7 and wherein the composition therein contains a substantial amount of water as a diluent.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-01-16 | 1976-07-17 | 1977-01-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-01-16 | 1980-07-17 | 1981-01-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-01-16 | 1984-07-17 | 1985-01-16 | $7700.00 | Window Closed / Lapsed |