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US3699963A Expired / Lapsed US ⏱️ 0.0 years remaining

Therapeutic adhesive patch

Assignee: Alza Corp
•
Filing: 1969-10-31
•
Granted: 1972-10-24
•
Expires: 1989-10-31
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Abstract

Abstract Therapeutic adhesive patch for stimulation of uterine contractions by application to the oral mucosa is comprised of a backing member, an amount of an oxytocic drug sufficient to release a therapeutically effective amount of the drug to the oral mucosa, and a pressure-sensitive adhesive coating. The oxytocic drug can be dispersed through or coated on the pressuresensitive adhesive; can be microencapsulated with a material permeable to passage of the drug and the microcapsules distributed throughout the pressure-sensitive adhesive; or can be incorporated in a reservoir layer permeable to passage of the drug and mounted on or laminated to the backing member and bearing a coating of the pressure-sensitive adhesive. The pressure-sensitive adhesive coating can cover the full-face surface of the adhesive patch or a part thereof, such as the perimeter of the face surface of the patch.

Inventors

  • 👤 Alejandro Zaffaroni

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 18:59
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61K9/0012; A61K9/0053; A61K9/006; A61K9/7069

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 35 words
The patch as defined by claim 1 wherein the backing member bears the pressure sensitive adhesive on one surface thereof and the reservoir comprises a plurality of discrete microcapsules distributed throughout the pressure sensitive adhesive.
Claim 2
Dependent Claim 28 words
The patch as defined by claim 2 wherein each of said microcapsule is comprised of an oxytocic drug formulation microencapsulated with the drug release rate controlling wall material.
Claim 3
Dependent Claim 34 words
The patch as defined by claim 2 wherein each of said microcapsule is comprised of a matrix of the drug release rate controlling wall material, said matrix having the oxytocic drug formulation distributed therethrough.
Claim 4
Dependent Claim 24 words
The patch as defined by claim 2 wherein the drug is selected from the group consisting of oxytocin, desamino-oxytocin, and pharmaceutically acceptable salts thereof.
Claim 5
Dependent Claim 36 words
The therapeutic patch as defined by claim 1 wherein the backing member bears a discrete, middle reservoir layer, and the pressure-sensitive adhesive is carried by the surface of the reservoir layer remote from the backing member.
Claim 6
Dependent Claim 24 words
The patch as defined by claim 6, wherein one outer surface of the wall member comprising the reservoir layer also defines the backing member.
Claim 7
Dependent Claim 25 words
The patch as defined by claim 6 wherein the reservoir layer is comprised of a walled container having an interior chamber containing the oxytocic drug.
Claim 8
Dependent Claim 31 words
The patch as defined by claim 6 wherein the reservoir layer is comprised of a matrix of the drug release rate controlling material, said matrix having the oxytocic drug distributed therethrough.
Claim 9
Dependent Claim 24 words
The patch as defined by claim 6 wherein the drug is selected from the group consisting of oxytocin, desamino-oxytocin, and pharmaceutically acceptable salts thereof.
Claim 10
Dependent Claim 23 words
The patch as defined by claim 6 wherein the pressure-sensitive adhesive coating extends only about the perimeter of the surface of the reservoir.
Claim 11
Dependent Claim 22 words
The patch as defined by claim 1 wherein the oxytocic drug is a pharmaceutically acceptable derivative thereof absorbable through the oral mucosa.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-10-24 1976-04-24 1976-10-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-10-24 1980-04-24 1980-10-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-10-24 1984-04-24 1984-10-24 $7700.00 Window Closed / Lapsed

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