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US3687949A Expired / Lapsed US ⏱️ 0.0 years remaining

Synthetic cephalosporins

Assignee: Bristol Myers Co
•
Filing: 1969-01-21
•
Granted: 1972-08-29
•
Expires: 1989-01-21
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Abstract

Abstract 7-( Alpha -3-Acylureidophenylacetamido)- and 7-( Alpha -3acylureidothienylacetamido)cephalosporanic acids and the corresponding betaines and desacetoxy derivatives are valuable as antibacterial agents, as nutritional supplements in animal feeds and as therapeutic agents in poultry and animals, including man, and are especially useful in the treatment of infectious diseases caused by Gram-positive and Gram-negative bacteria, most particularly those caused by the Pseudomonas genus. 7-(D- Alpha (3-(2''-furoyl)ureido)phenylacetamido)cephalosporanic acid, a preferred embodiment of the invention, is prepared by the treatment of 7-(D- Alpha -amino-phenylacetamido)cephalosporanic acid with 2-furoyl isocyanate.

Inventors

  • 👤 Charles Truman Holdrege

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 13:41
CPC Classifications
C; C07; C07D; C07D501/00; C07D501/14; C07D501/16; C07D501/20

Claims Analysis

Total Claims: 18
Claim 1
Independent Claim 5 words
A compound of the formula
Claim 2
Dependent Claim 11 words
A compound as defined in claim 2 wherein A is acetoxy.
Claim 3
Dependent Claim 11 words
A compound as defined in claim 2 wherein A is hydrogen.
Claim 4
Dependent Claim 11 words
A compound as defined in claim 2 wherein A is pyridinium.
Claim 5
Dependent Claim 20 words
A compound as defined in claim 2 wherein A is acetoxy and Z is phenyl, 2-thienyl, 3-thienyl, 2-furyl or 5-nitro-2-furyl.
Claim 6
Dependent Claim 20 words
A compound as defined in claim 2 wherein A is hydrogen and Z is phenyl, 2-thienyl, 3-thienyl, 2-furyl or 5-nitro-2-furyl.
Claim 7
Dependent Claim 20 words
A compound as defined in claim 2 wherein A is pyridinium and Z is phenyl, 2-thienyl, 3-thienyl, 2-furyl or 5-nitro-2-furyl.
Claim 8
Dependent Claim 11 words
A compound as defined in claim 6 in the D configuration.
Claim 9
Dependent Claim 11 words
A compound as defined in claim 7 in the D configuration.
Claim 10
Dependent Claim 11 words
A compound as defined in claim 8 in the D configuration.
Claim 11
Dependent Claim 10 words
The acid as defined in claim 9 of the formula
Claim 12
Dependent Claim 10 words
The acid as defined in claim 10 of the formula
Claim 13
Dependent Claim 10 words
The acid as defined in claim 9 of the formula
Claim 14
Dependent Claim 10 words
The compound as defined in claim 11 of the formula
Claim 15
Dependent Claim 10 words
The acid as defined in claim 9 of the formula
Claim 16
Dependent Claim 10 words
The compound as defined in claim 11 of the formula
Claim 17
Dependent Claim 10 words
The acid as defined in claim 9 of the formula
Claim 18
Dependent Claim 10 words
The compound as defined in claim 11 of the formula

References Cited (Backward Citations)

US3479339A Cited
US3497504A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-08-29 1976-02-28 1976-08-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-08-29 1980-02-28 1980-08-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-08-29 1984-02-28 1984-08-29 $7700.00 Window Closed / Lapsed

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