Blood component exchange device

Claim 2

A membrane type blood component transfer device comprising: a. a pair of substantially planar frames having open central areas, b. thin membranes adhered respectively to the one surface of one frame and to the opposite surface of the other, said frames being stacked on each other with their membranes confronting each other and in substantial contact to define a thin blood film flow space between them, c. the surface of a membrane which is remote from the blood film flow space and the central opening of the frame to which said membrane is adhered defining a gas flow recess, d. the said one frame having in the margin of its central opening oppositely located blood inlet and outlet ports for directing blood flow between the confronting membranes, e. the said other frame having in the margin of its central opening oppositely located fluid inlet and outlet ports for directing a fluid other than blood across said recess in contact with said blood remote surface of the membrane, f. a planar member superposed over said recess to enclose it, g. a fluid distribution element disposed on the blood remote surface of the membrane in said recess, said element being substantially flat, resilient and porous, h. said element being substantially coextensive with one dimension of said frame opening and less than the other dimension so as to leave narrow free spaces between the opposite margins of the opening and the element, said free spaces being equal substantially in length to the said one dimension, whereby said membranes can distend within limits into said free space to effect elongated blood channels near the edges of the membranes when the space between them is under blood pressure.

Claim 3

The device set forth in claim 1 wherein said fluid distribution element comprises: a. a substantially planar screen, and b. a thin layer of porous fibrous material surrounding said screen.

Claim 4

The device set forth in claim 1 wherein said fluid distribution element is characterized by having a parallelogram shape, whereupon said free spaces have a substantially triangular shape.

Claim 5

A membrane type blood component transfer device comprising: a. a pair of substantially planar frames having open central areas, b. thin membranes adhered respectively to the one surface of one frame and to the opposite surface of the other, said frames being stacked on each other with their membranes confronting each other and in substantial contact to define a thin blood film flow space between them, c. the surface of a membrane which is remote from the blood film flow space and the central opening of the frame to which said membrane is adhered defining a gas flow recess, d. the said one frame having in the margin of its central opening oppositely located blood inlet and outlet ports for directing blood flow between the confronting membranes, e. the said other frame having in the margin of its central opening oppositely located fluid inlet and outlet ports for directing a fluid other than blood across said recess in contact with said blood remote surface of the membrane, f. one of said planar frames having a notch in one of its edges extending into said frame opening, said notch being overlayed by a membrane, g. a blood distribution insert having a blood flow slot, said insert having a thickness substantially equal to the frame thickness and a shape similar to the notch, whereby the insert is pressed into the notch to depress the membrane for facilitating blood flow between the insert slot and the blood film space between the confronting membranes.

Claim 6

A membrane type blood component transfer device comprising: a. a pair of substantially planar frames having open central areas, b. thin membranes adhered respectively to the one surface of one frame and to the opposite surface of the other, said frames being stacked on each other with their membranes confronting each other and in substantial contact to define a thin blood film flow space between them, c. the surface of a membrane which is remote from the blood film flow space and the central opening of the frame to which said membrane is adhered defining a gas flow recess, d. the said one frame having in the margin of its central opening oppositely located blood inlet and outlet ports for directing blood flow between the confronting membranes, e. the said other frame having in the margin of its central opening oppositely located fluid inlet and outlet ports for directing a fluid other than blood across said recess in contact with said blood remote surface of the membrane, f. one of said planar frames having a notch in one of its edges extending into said frame opening, said notch being overlayed by a membrane, g. a blood distribution insert having a blood flow slot, said insert having a thickness substantially equal to the frame thickness and a shape similar to the notch, whereby the insert is pressed into the notch to depress the membrane for facilitating blood flow between the insert slot and the blood film space between the confronting membranes.

Claim 7

A membrane type blood gas exchange device comprising: a. respective pairs of thin planar substantially rectangular blood and gas frames each of which has a substantially rectangular central opening enclosed by the frame margins, b. a thin blood gas permeable membrane adhered to a surface of each respective frame, said frame pairs forming a blood envelope by being superposed on each other so that their membranes confront each other and create a blood film passageway at their interface, the blood remote surfaces of said membranes constituting the bottom of a gas flow recess whose depth is equal to the frame thickness, c. said gas frames having at least a pair of gas port notches communicating with said gas flow recess and at least a pair of blood flow holes extending through them, d. said blood frames having at least a pair of blood port notches communicating with the blood film passageway at the membrane interface and at least a pair of gas flow holes, e. said membranes all being perforated in line with said holes and notches, and said frames being stacked so that blood holes align with blood notches and gas holes align with gas notches, whereby to admit and exit blood and gas respectively in the space between the membranes and on the blood remote surface of the membranes, f. an imperforate planar member on one end of the stacked frames for enclosing said gas recess, and g. a planar member at the other end of the stacked frames, the member having blood and gas inlet and outlet holes aligned with the corresponding aforementioned holes in the frames, h. a gas distribution element disposed on the blood remote side of each membrane in the aforesaid recess, said element being substantially flat, resilient and porous, i. said element being substantially coextensive with one dimension of said frame opening and less than the other dimension so as to leave narrow free spaces between the opposite margins of the opening and the element, said free spaces being equal substantially in length to the said one dimension, whereby said membranes can distend with limits into said free space to effect elongated blood channels near the edges of the membranes when the space between them is under blood pressure.

Claim 8

A membrane type blood gas exchange device comprising: a. respective pairs of thin planar substantially rectangular blood and gas frames each of which has a substantially rectangular central opening enclosed by the frame margins, b. a thin blood gas permeable membrane adhered to a surface of each respective frame, said frame pairs forming a blood envelope by being superposed on each other so that their membranes confront each other and create a blood film passageway at their interface, the blood remote surfaces of said membranes constituting the bottom of a gas flow recess whose depth is equal to the frame thickness, c. said gas frames having at least a pair of gas port notches communicating with said gas flow recess and at least a pair of blood flow holes extending through them, d. said blood frames having at least a pair of blood port notches communicating with the blood film passageway at the membrane interface and at least a pair of gas flow holes, e. said membranes all being perforated in line with said holes and notches, and said frames being stacked so that blood holes align with blood notches and gas holes align with gas notches, whereby to admit and exit blood and gas respectively in the space between the membranes and on the blood remote surface of the membranes, f. an imperforate planar member on one end of the stacked frames for enclosing said gas recess, and g. a planar member at the other end of the stacked frames, the member having blood and gas inlet and outlet holes aligned with the corresponding aforementioned holes in the frames, h. a gas distribution element disposed on the blood remote side of each membrane in the aforesaid recess, said element being substantially flat, resilient and porous, i. said element being substantially coextensive with one dimension of said frame opening and less than the other dimension so as to leave narrow free spaces between the opposite margins of the opening and the element, said free spaces being equal substantially in length to the said one dimension, whereby said membranes can distend with limits into said free space to effect elongated blood channels near the edges of the membranes when the space between them is under blood pressure.

Claim 9

A membrane type blood gas exchange device comprising: a. respective pairs of thin planar substantially rectangular blood and gas frames each of which has a substantially rectangular central opening enclosed by the frame margins, b. a thin blood gas permEable membrane adhered to a surface of each respective frame, said frame pairs forming a blood envelope by being superposed on each other so that their membranes confront each other and create a blood film passageway at their interface, the blood remote surfaces of said membranes constituting the bottom of a gas flow recess whose depth is equal to the frame thickness, c. said gas frames having at least a pair of gas port notches communicating with said gas flow recess and at least a pair of blood flow holes extending through them, d. said blood frames having at least a pair of blood port notches communicating with the blood film passageway at the membrane interface and at least a pair of gas flow holes, e. said membranes all being perforated in line with said holes and notches, and said frames being stacked so that blood holes align with blood notches and gas holes align with gas notches, whereby to admit and exit blood and gas respectively in the space between the membranes and on the blood remote surface of the membranes, f. an imperforate planar member on one end of the stacked frames for enclosing said gas recess, and g. a planar member at the other end of the stacked frames, the member having blood and gas inlet and outlet holes aligned with the corresponding aforementioned holes in the frames, h. said blood port notches being overlayed by membranes, i. a blood distribution insert having a laterally directed blood flow slot, said insert having a thickness substantially equal to the blood frames and being shaped to register with blood port notches, whereby the insert is pressed into the notches to depress the membrane for facilitating blood flow between the inserts slots and the blood film space between the membranes.

Claim 10

A membrane type blood gas exchange device comprising: a. respective pairs of thin planar substantially rectangular blood and gas frames each of which has a substantially rectangular central opening enclosed by the frame margins, b. a thin blood gas permEable membrane adhered to a surface of each respective frame, said frame pairs forming a blood envelope by being superposed on each other so that their membranes confront each other and create a blood film passageway at their interface, the blood remote surfaces of said membranes constituting the bottom of a gas flow recess whose depth is equal to the frame thickness, c. said gas frames having at least a pair of gas port notches communicating with said gas flow recess and at least a pair of blood flow holes extending through them, d. said blood frames having at least a pair of blood port notches communicating with the blood film passageway at the membrane interface and at least a pair of gas flow holes, e. said membranes all being perforated in line with said holes and notches, and said frames being stacked so that blood holes align with blood notches and gas holes align with gas notches, whereby to admit and exit blood and gas respectively in the space between the membranes and on the blood remote surface of the membranes, f. an imperforate planar member on one end of the stacked frames for enclosing said gas recess, and g. a planar member at the other end of the stacked frames, the member having blood and gas inlet and outlet holes aligned with the corresponding aforementioned holes in the frames, h. said blood port notches being overlayed by membranes, i. a blood distribution insert having a laterally directed blood flow slot, said insert having a thickness substantially equal to the blood frames and being shaped to register with blood port notches, whereby the insert is pressed into the notches to depress the membrane for facilitating blood flow between the inserts slots and the blood film space between the membranes.

Claim 11

The device set forth in claim 5 wherein said gas distribution element comprises: a. a substantially planar screen, and b. a thin layer of porous fibrous material surrounding said screen.