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US3683635A Expired / Lapsed US ⏱️ 0.0 years remaining

Freeze stabilized insulin

Assignee: Individual
•
Filing: 1970-12-07
•
Granted: 1972-08-15
•
Expires: 1990-12-07
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Abstract

Abstract The present invention provides a process whereby the drug insulin can be stored for an indefinite period of time without any loss of its physical, chemical or pharmaceutical characteristics. The drug solution is instantly frozen as, for example, in liquid nitrogen, and stored below the solution freezing point until it is needed. It is then thawed and ready for use. Its efficacy has been proved on rabbits and a depancreatized dog.

Inventors

  • 👤 Mario Campanelli

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 18:46
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/575; C07K14/62; C07K14/625

Claims Analysis

Total Claims: 1
Claim 1
Independent Claim 39 words
the method of stabilizing aqueous injectable insulin compositions comprising immersing the compositions in liquid nitrogen for a period of at least about 3 seconds per cc of insulin composition, and storing said compositions at a temperature below about 10*F.

References Cited (Backward Citations)

US2380339A Cited
US2655007A Cited
US2659986A Cited
US2875588A Cited
US3092974A Cited
US3303662A Cited
US3347745A Cited
US3431745A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-08-15 1976-02-14 1976-08-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-08-15 1980-02-14 1980-08-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-08-15 1984-02-14 1984-08-15 $7700.00 Window Closed / Lapsed

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