US3678154A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oral compositions for calculus retardation
Assignee: Procter and Gamble Co
•
Filing: 1968-07-01
•
Granted: 1972-07-18
•
Expires: 1988-07-01
Abstract
Abstract Oral compositions, such as toothpaste, mouthwash, and the like, containing certain polyphosphonates as anticalculus agents, and a water-soluble source of fluoride ions to counteract the adverse effects of such polyphosphonates on post eruptive maturation of dental enamel.
Inventors
- 👤 James S Widder
- 👤 William W Briner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 23:01
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21; A61K8/30; A61K8/55; A61Q; A61Q11/00; C; C07; C07F; C07F9/00; C07F9/02; C07F9/28; C07F9/38; C07F9/3804; C07F9/3839
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
20 words
An oral composition in accordance with claim 1 wherein the polyphosphonate is ethane-1-hydroxy-1,1-diphosphonic acid or a pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim
20 words
An oral composition in accordance with claim 1 wherein the polyphosphonate is methanediphosphonic acid or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
20 words
An oral composition in accordance with claim 1 wherein the polyphosphonate is methanedichlorodiphosphonic acid or a pharmaceutically acceptable salt thereof.
Claim 4
Dependent Claim
20 words
An oral composiTion in accordance with claim 1 wherein the polyphosphonate is methanehydroxydiphosphonic acid or a pharmaceutically acceptable salt thereof.
Claim 5
Dependent Claim
20 words
An oral composition in accordance with claim 1 wherein the polyphosphonate is phenylaminomethanediphosphonic acid or a pharmaceutically acceptable salt thereof.
Claim 6
Dependent Claim
18 words
An oral composition in accordance with claim 1 wherein the water-soluble source of fluoride ion is sodium fluoride.
Claim 7
Dependent Claim
18 words
An oral composition in accordance with claim 1 wherein the water-soluble source of fluoride ion is stannous fluoride
Claim 8
Dependent Claim
70 words
In a toothpaste composition having a pH within the range from about 5.0 to about 11.0 and containing from about 20 percent to about 60 percent by weight of a dentifrice abrasive and from about 1.5 percent to about 3 percent by weight of an anticalculus agent which interferes with calcium hydroxyapatite crystal growth thereby impeding maturation of dental enamel, said anticalculus agent being selected from the group consisting of
Claim 9
Dependent Claim
20 words
A toothpaste composition in accordance with claim 9 wherein the polyphosphonate is ethane-1-hydroxy-1,1-diphosphonic acid or a pharmaceutically acceptable salt thereof.
Claim 10
Dependent Claim
18 words
A toothpaste composition in accordance with claim 9 wherein the water-soluble source of fluoride ion is sodium fluoride.
Claim 11
Dependent Claim
58 words
In a mouthwash composition having a pH within the range from about 5.0 to about 11.0 and containing water ethanol and glycerine and from about 0.1% to about 5.0% by weight of an anticalculus agent which interferes with calcium hydroxyapatite crystal growth thereby impeding maturation of dental enamel, said anticalculus agent being selected from the group consisting of
Claim 12
Dependent Claim
98 words
In a toothpaste composition having a pH within thE range from about 6.0 to 7.5 and containing from about 1.5 to 3.0 percent by weight of an anticalculus agent selected from the group consisting of ethane-1-hydroxy-1,1-diphosphonic acid and the pharmaceutically acceptable salts thereof, the improvement which comprises incorporating therein a non-toxic water-soluble source of fluoride ion in a quantity sufficient to provide a mole ratio of said anticalculus agent to fluoride ion within the range from about 0.1:1 to about 5.0 to 1.0, thereby promoting maturation of dental enamel and rendering said composition suitable for use by children.
References Cited (Backward Citations)
US2191199A
Cited
US3251800A
Cited
US3303139A
Cited
US3159581A
Cited
US3299123A
Cited
US3429914A
Cited
US3463835A
Cited
US3400176A
Cited
US3488419A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-07-18 | 1976-01-17 | 1976-07-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-07-18 | 1980-01-17 | 1980-07-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-07-18 | 1984-01-17 | 1984-07-18 | $7700.00 | Window Closed / Lapsed |