US3674844A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Salicylic acid derivatives
Assignee: Merck and Co Inc
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Filing: 1970-04-20
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Granted: 1972-07-04
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Expires: 1990-04-20
Abstract
Abstract New substituted salicylic acids and non-toxic pharmaceutically acceptable salts, esters, and amides derived therefrom. The substituted salicylic acids described herein are useful as antiinflammatory compounds. Also included herein are methods of preparing said salicylic acid compounds, pharmaceutical compositions having said salicylic acid compounds as an active ingredient and methods of treating inflammation by administering these particular compositions to patients.
Inventors
- 👤 Tsung-Ying Shen
- 👤 Howard Jones
- 👤 Bruce E Witzel
- 👤 Gordon L Walford
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 09:40
CPC Classifications
C; C07; C07C; C07C229/00; C07C229/38
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
57 words
A compound of the formula: wherein R is hydroxy; R2 is hydrogen or loweralkyl; R3 is hydrogen, loweralkyl, or fluoro; X is loweralkoxy, fluoro, trifluoromethyl or diloweralkylamino; and Y is selected from the group of methyleneimino (-CH2NH-), iminomethylene (-NHCH2-), methylidenenitrilo (-CH=N-), nitrilomethylidene (-N=CH-), and carbonylimino ; provided that the OR2 group is always ortho to the group.
Claim 2
Dependent Claim
2 words
4-(p-fluorobenzylideneamino)-salicylic acid.
Claim 3
Dependent Claim
2 words
5-(p-fluorobenzylamino)-salicylic acid.
Claim 4
Dependent Claim
2 words
5-(p-fluorobenzamido)-salicylic acid.
Claim 5
Dependent Claim
2 words
4-(p-fluoroanilinomethyl)-salicylic acid.
Claim 6
Dependent Claim
2 words
5-(p-fluorophenyliminomethyl)-salicylic acid.
Claim 7
Dependent Claim
23 words
A compound of the formula: wherein X is fluoro or chloro, provided that the hydroxy group is always ortho to the carboxy group.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-07-04 | 1976-01-03 | 1976-07-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-07-04 | 1980-01-03 | 1980-07-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-07-04 | 1984-01-03 | 1984-07-04 | $7700.00 | Window Closed / Lapsed |