US3674799A
Expired / Lapsed
US
⏱️ 0.0 years remaining
(4'-(phenyl-3 6-dihydro-1-(2h)-pyridyl)-2-hydroxy propoxy-anilides and derivatives thereof
Assignee: F Hoffmann La Roche AG
•
Filing: 1969-12-04
•
Granted: 1972-07-04
•
Expires: 1989-12-04
Abstract
Abstract Substituted (3-(4-phenyl-1-hydropyridyl)-propoxy or propylthio)anilines prepared, inter alia, by reacting the correspondingly substituted propoxy or propyl-thio anilines and N-phenyl-hydropyridines, are described. The end products, i.e., the substituted (3-(4-phenyl-1-hydropyridyl)-propoxy or propylthio)anilines are useful as antiphlogistic, antiallergic, antitussive and analgesic agents.
Inventors
- 👤 Albrecht Edenhofer
- 👤 Hans Spiegelberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 13:34
CPC Classifications
C; C07; C07D; C07D303/00; C07D303/02; C07D303/12; C07D303/18; C07D303/20; C07D303/22; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/40; C07D211/44; C07D211/52; C07D211/68; C07D211/70; C07D303/34
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
11 words
A compound in accordance with claim 1, wherein Y is hydroxymethylene.
Claim 2
Dependent Claim
19 words
A compound in accordance with claim 2, wherein R1 is lower alkanoylamido; R2 is hydrogen and R3 is halogen.
Claim 3
Dependent Claim
17 words
A compound in accordance with claim 3, wherein R1 is p-propionamido, R3 is p-fluoro, i.e., rac.-4''-(3-(4-(p-fluoro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-2-hydroxy -propoxy)-propionanilide.
Claim 4
Dependent Claim
18 words
A compound in accordance with claim 3, wherein R1 is p-acetamido; R3 is p-fluoro, i.e., rac.-4''-( 3-(4-(p-fluoro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-2-hydroxy-propoxy) -acetanilide.
Claim 5
Dependent Claim
17 words
A compound in accordance with claim 3, wherein R1 is p-isobutyramido; R3 is p-fluoro, i.e., rac.-4''-)3-(4-(p-fluoro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-2-hydroxy -propoxy)-isobutyranilide.
Claim 6
Dependent Claim
9 words
A compound in accordance with claim 6, (-)-4''(3-(4-(p-fluoro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-2-hydroxy-propoxy) -isobutyranilide.
Claim 7
Dependent Claim
9 words
A compound in accordance with claim 6, (+)-4''(3-(4-(p-fluoro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-2-hydroxy-propoxy) -isobutyranilide.
Claim 8
Dependent Claim
11 words
A compound in accordance with claim 1, wherein Y is methylene.
Claim 9
Dependent Claim
19 words
A compound in accordance with claim 9, wherein R1 is lower alkanoylamido; R2 is hydrogen; and R3 is halogen.
Claim 10
Dependent Claim
9 words
A compound in accordance with claim 10, rac. 4''-(3-(4-(p-chloro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-propoxy)acetanilide.
Claim 11
Dependent Claim
9 words
A compound in accordance with claim 1, rac.2''(3-(4-(p-chloro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-2-hydroxy -propoxy)acetanilide.
Claim 12
Dependent Claim
9 words
A compound in accordance with claim 1, rac.-2''-(3-(4-(p-fluoro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-2-hydroxy -propoxy)acetanilide.
Claim 13
Dependent Claim
8 words
A compound in accordance with claim 1, rac.-p-(3-(4-(p-fluoro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-2-hydroxy-propoxy)-aniline.
Claim 14
Dependent Claim
9 words
A compound in accordance with claim 1, rac.-4''-(3-(4-(p-fluoro-phenyl)-3,6-dihydro-1(2H)-pyridyl)-2-hydroxy -propoxy)methanesulfonanilide.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-07-04 | 1976-01-03 | 1976-07-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-07-04 | 1980-01-03 | 1980-07-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-07-04 | 1984-01-03 | 1984-07-04 | $7700.00 | Window Closed / Lapsed |