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US3666763A Expired / Lapsed US ⏱️ 0.0 years remaining

4-phenyl isoquinolines and process for preparing same

Assignee: F Hoffmann La Roche AG
•
Filing: 1970-01-06
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Granted: 1972-05-30
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Expires: 1990-01-06
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Abstract

Abstract Substituted 4-phenylisoquinolines prepared from the correspondingly substituted 4-phenyl-4-isoquinolinols are described. The end products are useful as antidepressants and hypotensive agents.

Inventors

  • 👤 Guenter Grethe
  • 👤 Milan Radoje Uskokovic

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 19:35
CPC Classifications
C; C07; C07D; C07D217/00; C07D217/02; C07D217/04; C07D217/10; C07D217/22; C07D217/24

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 1 words
1,2,3,4-tetrahydro-7-methoxy-1,2-dimethyl-4-phenylisoquinoline.
Claim 2
Dependent Claim 1 words
1,2,3,4-tetrahydro-7-methoxy-2-methyl-4-(4-tolyl)-isoquinoline.
Claim 3
Dependent Claim 1 words
1,2,3,4-tetrahydro-7-methoxy-2-methyl-4-phenylisoquinoline.
Claim 4
Dependent Claim 1 words
1,2,3,4-tetrahydro-7-methoxy-2-methyl-4(S)-phenylisoquinoline.
Claim 5
Dependent Claim 1 words
1,2,3,4-tetrahydro-7-methoxy-2-methyl-4(R)-phenylisoquinoline.
Claim 6
Dependent Claim 1 words
1,2,3,4-tetrahydro-7-methoxy-4(S)-phenylisoquinoline.
Claim 7
Dependent Claim 1 words
1,2,3,4-tetrahydro-7-methoxy-4(R)-phenylisoquinoline.
Claim 8
Dependent Claim 10 words
A process for the preparation of compounds of the formula
Claim 9
Dependent Claim 16 words
The process of claim 9 wherein said catalytic hydrogenating agent is palladium (10 percent) on carbon.

References Cited (Backward Citations)

US2759936A Cited
US3457266A Cited
US3393198A Cited
US3553218A Cited
GB1164192A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-05-30 1975-11-29 1976-05-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-05-30 1979-11-29 1980-05-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-05-30 1983-11-29 1984-05-30 $7700.00 Window Closed / Lapsed

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