Mucolytic composition and method of treatment of broncho-pulmonary disorders therewith
Abstract
Abstract PHARMACEUTICALLY ACTIVE COMPOSITIONS FOR TREATMENT OF BRONCHO-PULMONARY DISORDERS CONTAINING AN N-SUBSTITUTED CYSTEINE DERIVATIVE TOGETHER WITH DESOXYRIBONUCLEASE, BOTH OF WHICH ACT AS MUCOLYTIC AGENTS, EACH ON ITS RESPECTIVE SUBSTRATE. IT IS KNOWN THAT CERTAIN COMPOUNDS CONTAINING FREE MERCAPTO GROUPS CAN BE USED AS MUCOLYTIC AGENTS IN THE TREATMENT OF PULMMONARY DISORDERS. SUCH COMPOUNDS LOWER THE VISCOSITY OF RESPIRATORY MUCOUS SECRETIONS BY A MECHANISM INVOLVING THE CLEAVAGE OF DISULFIDE LINKAGES OF MUCORPROTEIN. IT IS ALSO KNOWN THAT DESOXYRIBONUCLEASE TREATMENT OF PULMONARY DISORDERS. SUCH COMPOUNDS RAPIDLY DEGRADES DESOXYRIBONUCLEOPROTEIN (AND DESOXYRIBONUCLEIC ACID), THUS DECREASING THE VISCOSITY OF PURULENT MATERIAL.
Inventors
- 👤 Hermann J Eichel
- 👤 Kenneth R Hickey
- 👤 Frank R Springman
Bibliographic Details
Claims Analysis
Total Claims: 0References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-05-16 | 1975-11-15 | 1976-05-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-05-16 | 1979-11-15 | 1980-05-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-05-16 | 1983-11-15 | 1984-05-16 | $7700.00 | Window Closed / Lapsed |