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US3663552A Expired / Lapsed US ⏱️ 0.0 years remaining

2'-substituted-cinchona alkaloids

Assignee: Wyeth LLC
•
Filing: 1970-04-09
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Granted: 1972-05-16
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Expires: 1990-04-09
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Abstract

Abstract 2''-SUBSTITUTED ALKALOIDS OF THE CINCHONA SERIES, ESPECIALLY 2''-SUBSTITUTED QUININE, QUINIDINE, CINCHONIE, CINCHONIDINE AND DIHYDRO ANALOGS OF FORMULAS I AND II, AND THEIR SALTS, ARE PREPARED BY TREATING AR-N-OXIDES OF THE ALKALOIDS WITH THE CORRESPONDING ORGANOMETALLIC REAGENT AND, IF DESIRED, CONVERTING THE FREE BASES THUS FORMED INTO PHARMACEUTICALLY-ACCEPTABLE ACID-ADDITION SALTS. THE NEW COMPOUNDS ARE PHARMACOLOGICALLY ACTIVE, ESPECIALLY ANTIMALARIALLY AND ANTI-ARRHYTHMICALLY.

Inventors

  • 👤 John P Yardley
  • 👤 Royal E Bright
  • 👤 Richard W Rees
  • 👤 Herchel Smith

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 01:25
CPC Classifications
C; C07; C07D; C07D453/00; C07D453/02; C07D453/04

Claims Analysis

Total Claims: 0
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References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-05-16 1975-11-15 1976-05-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-05-16 1979-11-15 1980-05-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-05-16 1983-11-15 1984-05-16 $7700.00 Window Closed / Lapsed

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