Diphenyl amine urea derivatives
Abstract
Abstract DIPHENYL AMINE DERIVATIVES OF THE FORMULA 1-((R1-PHENYL)-NH-),R2,4-(R3-CO-NH-)BENZENE WHEREIN EACH OF R1 AND R2 CAN BE HYDROGEN, HALOGEN, HYDROXY, LOWER ALKYL OR LOWER ALKOXY AND R3 IS LOWER ALKYL OR ALKENYL OF UP TO6 CARBON ATOMS; PYRIDYL; PHENYL OR PYRIDYL SUBSTITUTED WITH HALOGEN, HYDROXY, AMINO, LOWER ALKOXY OR LOWER ALKYL; LOWER ALKOXY WITH 1 TO 6 CARBON ATOMS; MONO AND DIALKYL AMINO GROUPS WHEREIN ALKYL IS OF 1 TO 6 CARBON ATOMS IN WHICH THE ALKYL GROUPS CAN BE CLOSED, IF DESIRED, WITH ANOTHER HETEROATOM TO A 5,6 OR 7 MEMBERED RING AS IN PYRROLIDONE, PIPERIDINE MORPHOLINE, PIPERAZINE AND HOMOPIPERAZINE AND ANY PRIMARY AMINO GROUPS PRESENT CAN, IF DESIRED, BE ACYLATED WITH LOW MOLECULAR WEIGHT ORGANIC ACIDS SUCH AS THE ALKANOIC ACIDS OR DERIVATIVES OF CARBONIC ACID AND THEIR ACID ADDITION SALTS. THE COMPOUNDS HAVE GOOD ANTI-INFLAMMATORY, ANALGESTIC AND ANTI-PYRETIC ACTION.
Inventors
- 👤 Kurt Thiele
Bibliographic Details
Claims Analysis
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