Phenoxy carboxylic acid derivatives
Abstract
Abstract X-C(-R1)(-R2)-CO-A WHEREIN A, B, R1 AND R2 ARE THE SAME AS DEFINED ABOVE AND X IS HALOGEN OR HYDROXYL, AND IF NECESSARY, ESTERIFYING OR HYDROLYZING THE RESULTING CONDENSATIN PRODUCT. IN THE PRESENCE OF AN ALKALI. ALTERNATIVELY, THEY ARE PRODUCED BY REACTING THE PHENOL DERIVATIVE WITH A CARBOXYLIC ACID DERIVATIVE OF THE FORMULA, (B-PHENYL)-O-C(-R1)(-R2)-CO-A WHEREIN R1 AND R2 EACH IS HYDROGEN OR LOWER ALKYL, A IS HYDROXYL OR ALKOXY; AND B IS CYCLOALKENYL, 2-BENZOTHIAZOLYL OR 2-BENZOXAZOLYL. THESE COMPOUNDS ARE PREPARED BY REACTING A PHENOL DERIVATIVE OF THE FORMULA, B-PHENOL WITH CHLOROFORM AND A CARBONYL COMPOUND OF THE FORMULA, R1-CO-R2 NOVEL ANTI-ATHEROSCLEROSIS AGENTS OF THE FORMULA,
Inventors
- 👤 Yasushi Nakamura
- 👤 Kunio Agatsuma
- 👤 Yoshihiro Tanaka
- 👤 Shunji Aono
Bibliographic Details
Claims Analysis
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