Certain pyridyl-1 2 4-oxadiazole derivatives
Abstract
Abstract A 1,2,4-OXADIAZOLE FOR USE AS A PHARMACEUTICALLY ACTIVE AGENT WITH SPASMOLYTIC, ANTIPYRETIC, ANALGESIC, HYPNOTIC OR ANTIRHEUMATIC PROPERTIES. THE COMPOUND IS OF THE FORMULA 3-R1,5-R2-1,2,4-OXADIAZOLE WHEREIN R1 CONSISTS OF 2-PYRIDYL, 3-PYRIDYL OR 4-PYRIDYL UNSUBSTITUTED OR SUBSTITUTED WITH AN ALKYL GROUP HAVING 1 TO 6 CARBON ATOMS, AND WHEREIN R2 IS PHENYL, HALOPHENYL AMINOPHENYL, HYDROXYPHENYL OR CHLOROPHENOXYMETHYL. THE APPLICATION ALSO DISCLOSES THE HYDROCHLORIDE, HYDROBROMIDE, SULFATE, PHOSPHATE, MALEATE, LACTATE, ACETATE OR TARTARATE ACID-ADDITION SALT OF THE 1,2,4-OXADIAZOLE AND ITS ALKYHALOGENIDE-QUATERNIZED OR ALKYLSULFATEQUATERENIZED PHARMACEUTICALLY ACCEPTABLE SALT WHEREIN THE ALKYL GROUP OF THE QUATERNIZING COMPOUND CONTAINS 1 TO 6 CARBON ATOMS.
Inventors
- 👤 Kalman Harsanyi Jozsef Reiter
- 👤 Dezso Korbonits
- 👤 Csaba Gonczi
- 👤 Kalman Takacs
- 👤 Erzsebet Bako
- 👤 Gyorgy Leszkovszky
- 👤 Laszlo Tardos
- 👤 Csaba Vertesy
Bibliographic Details
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