1-(cyanophenoxy)-2-hydroxy-3-sec.-alkylamino-propanes
Abstract
Abstract RACEMIC MIXTURES AND OPTICALLY ACTIVE ISOMERS OF 1PHENOXY - 2- HYDROXY -3- SEC, - ALKYLAMINO - PROPANES OF THE FORMULA R,R1,(R2-CH(-R3)-NH-CH2-CH(-OH)-CH2-O-)BENZENE WHEREIN R IS SELECTED FROM THE GROUP CONSISTING OF -(CH2)X-CN -(CH2)X-NH2 AND -(CH2)X+1-OH WHERE X IS 0,1, 2 OR 3, CARBOXYL, ALKOXYCARBONYL OR 1 TO 5 CARBON ATOMS OF THE ALKOXYL PART AND ALKENYLOXY AND ALKYNYLOXY OF 2 TO 5 CARBON ATOMS, R1 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, HALOGEN, LOWER ALKYL AND LOWER ALKOXY OF 1 TO 5 CARBON ATOMS, LOWER ALKENYL OF 2 TO 5 CARBON ATOMS, CYANO AND NITRO AND R AND R1 TAKEN TOGETHER MAY BE METHYLENEDIOXY, R2 IS AN ALKYL OF 1 TO 5 CARBON ATOMS AND R3 IS ALKYL OR 2 TO 6 CARBON ATOMS AND THEIR NON-TOXIC, PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS HAVING B-ADRENOLYTIC AND BLOOD PRESSURE REDUCING PROPERTIES.
Inventors
- 👤 Herbert Koppe
- 👤 Werner Kummer
- 👤 Helmut Stahle
- 👤 Karl Zeile
- 👤 Werner Traunecker
Bibliographic Details
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