1-amino-3 4-dihydroisoquinolines
Abstract
Abstract THE 3,4-DIHYDROISOQUINOLINE DERIVATIVES OF THE FORMULA: 1-(R1-N(-R2)-A-),6,7-DI(R-)-3,4-DIHYDROISOQUINOLINE WHEREIN THE SYMBOLS R REPRESENT HYDROGEN, HALOGEN OR METHOXY OR TOGETHER FORM A METHYLENEDIOXY GROUP, A REPRESENTS A SINGLE BONC OR A GROUPING -S-A1- LINKED BY THE SULPHUR ATOM TO THE ISOQUINOLINE NUCLEUS AND A1 REPRESENTS AN ALKYLENE GROUP OF 1 THROUGH 5 CARBON ATOMS, AND R1 AND R2 REPRESENTS HYDROGEN, ALKYL, HALOGENOALKYL, HYDROXYALKYL, CYANOALKYL, DIALKYLAMINOALKYL, 4-METHYL-1-PIPERAZINYLALKYL,ARALKYL, AMINO, THIOUREIDO, OR A C-LINKED NITROGEN-CONTAINING 5- OR 6-MEMBERED MONONUCLEAR HETEROCYCLYL GROUP, OR R1 AND R2 TOGETHER WITH THE NITROGEN ATOM TO WHICH THEY ARE ATTACHED COLLECTIVLEY REPRESENT A 5- OR 6-MEMBERED MONONUCLEAR HETEROCYCLIC GROUP, ARE USEFUL AS THERAPEUTICS, POSSESSING IN PARTICULAR ANT-TUSSIVE AND ANTI-FIBRILLATING PROPERTIES.
Inventors
- 👤 Claude Jeanmart
- 👤 Mayer Naoum Messer
- 👤 Pierre Edouard Simon
Bibliographic Details
Claims Analysis
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