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US3630840A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for purifying solutions of the foot-and-mouth disease virus

Assignee: Bayer AG
•
Filing: 1970-03-13
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Granted: 1971-12-28
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Expires: 1990-03-13
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Abstract

Abstract Foot-and-mouth disease virus solutions, used for the preparation of vaccines against the disease, are freed of undesirable protein contaminants accompanying the virus particles by subjecting the impure solution to fractional precipitation with polyethylene glycol solutions. The precipitate, containing the virus intigens is separated from the liquid phase which contains the proteins, preferably by centrifuging. The sediment consists of substantially purified virus antigen.

Inventors

  • 👤 Otto Wagner
  • 👤 Horst Geilhausen
  • 👤 Hans Bahnemann
  • 👤 Otto-Erich Schweckendiek

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 13:05
CPC Classifications
C; C12; C12N; C12N7/00; A; A61; A61K; A61K39/00; A61K39/12; A61K39/125; A61K39/135; C12N2770/00; C12N2770/00011; C12N2770/32011; C12N2770/32111; C12N2770/32134; C12N2770/32151; Y; Y10; Y10S; Y10S530/00; Y10S530/806; Y10S530/82; Y10S530/826

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 16 words
The process of claim 1 carried out at a temperature between 0* C. and room temperature.
Claim 2
Dependent Claim 22 words
The process of claim 1 carried out at a pH of about 8.5 and a temperature of from 4* to 5* C.
Claim 3
Dependent Claim 30 words
The process of claim 1 wherein after addition of the polyethylene glycol solution the mixture is permitted to stand for 12 to 60 hours, then separating the precipitate by centrifuge.

References Cited (Backward Citations)

US3415804A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1974-12-27 1975-06-28 1975-12-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1978-12-27 1979-06-28 1979-12-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1982-12-27 1983-06-28 1983-12-28 $7700.00 Window Closed / Lapsed

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