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US3627698A Expired / Lapsed US ⏱️ 0.0 years remaining

Hydroperoxide diagnostic agents containing a chromogen indicator

Assignee: Roche Diagnostics GmbH
•
Filing: 1970-03-20
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Granted: 1971-12-14
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Expires: 1990-03-20
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Abstract

Abstract D R A W I N G

Inventors

  • 👤 Hans-Georg Rey
  • 👤 Hans Wielinger
  • 👤 Peter Rieckmann

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 20:34
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/28; C12Q1/54; C12Q2326/00; C12Q2326/30; Y; Y10; Y10S; Y10S435/00; Y10S435/803; Y10T; Y10T436/00; Y10T436/20; Y10T436/206664

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 47 words
Diagnostic agent according to claim 1 for use in the determination of hydroperoxide or a substance which reacts with the liberation of hydrogen peroxide comprising a member selected from the group consisting of peroxidase and a peroxidatively active substance and a chromogen as defined in claim 1.
Claim 2
Dependent Claim 39 words
Diagnostic agent according to claim 1 for use in the determination of peroxidatively active substances comprising a member selected from the group consisting of hydrogen peroxide and substances forming hydrogen peroxide and a chromogen as defined in claim 1.
Claim 3
Dependent Claim 31 words
Diagnostic agent as claimed in claim 1 wherein one, and only one, of the X groups in the formula is oxygen or a carbon atom substituted with two lower alkyl groups.
Claim 4
Dependent Claim 28 words
Diagnostic agent as claimed in claim 1 wherein neither of the X groups in the formula is oxygen or a carbon atom substituted with two lower alkyl groups.
Claim 5
Dependent Claim 18 words
Diagnostic agent according to claim 1 in the form of a test paper impregnated with said diagnostic agent.
Claim 6
Dependent Claim 18 words
Diagnostic agent according to claim 1 in the form of a test film impregnated with said diagnostic agent.
Claim 7
Dependent Claim 13 words
Diagnostic agent according to claim 1 in the form of a solution thereof.
Claim 8
Dependent Claim 107 words
Diagnostic agent according to claim 1 additionally containing a compound having the formula: wherein Ar is a member selected from the group consisting of benzene and naphthalene nuclei, V is a member selected from the group consisting of hydroxyl and amino, v'' is a member selected from the group consisting of hydrogen, hydroxy, Amino, alkylated amino and arylated amino, W is a member selected from the group consisting of amino, carboxy, alkyl, alkoxy, aryl and sulfonic acid groups and W'' is a member selected from the group consisting of hydrogen, amino, carboxy, alkyl, alkoxy, aryl, sulfonic acid groups and alkali metal carboxylate or sulfonate groups, as modifier.
Claim 9
Dependent Claim 107 words
Diagnostic agent according to claim 2 additionally containing a compound having the formula: wherein Ar is a member selected from the group consisting of benzene and naphthalene nuclei, V is a member selected from the group consisting of hydroxyl and amino, V'' is a member selected from the group consisting of hydrogen, hydroxy, amino, alkylated amino and arylated amino, W is a member selected from the group consisting of amino, carboxy, alkyl, aryl, alkoxy and sulfonic acid groups and W'' is a member selected from the group consisting of hydrogen, amino, carboxy, alkyl alkoxy, aryl, sulfonic acid groups and alkali metal carboxylate or sulfonate groups, as modifier.
Claim 10
Dependent Claim 107 words
Diagnostic agent according to claim 3 additionally containing a compound having the formula: wherein Ar is a member selected from the group consisting of benzene and naphthalene nuclei, V is a member selected from the group consisting of hydroxyl and amino, V'' is a member selected from the group consisting of hydrogen, hydroxy, amino, alkylated amino and arylated amino, W is a member selected from the group consisting of amino, carboxy, alkyl, alkoxy, aryl and sulfonic acid groups and W'' is a member selected from the group consisting of hydrogen, amino, carboxy, alkyl, alkoxy, aryl, sulfonic acid groups and alkali metal carboxylate or sulfonate groups, as modifier.
Claim 11
Dependent Claim 13 words
Diagnostic agent according to claim 1 wherein said chromogen (I) is 2,2''-azino-di-(3-ethyl-benzthiazolone-6-sulfonic acid).
Claim 12
Dependent Claim 12 words
Diagnostic agent according to claim 1 wherein said chromogen (I) is 2,2''-azino-di-(1-ethyl-quinoline-6-sulfonic-acid).
Claim 13
Dependent Claim 19 words
Diagnostic agent according to claim 9 wherein said chromogen (I) is 2,2''-azino-di-(1-ethyl-quinoline-6-sulfonic acid) and said modifier is o-amino-phenol-p-sulfonic acid.
Claim 14
Dependent Claim 19 words
Diagnostic agent according to claim 9 wherein said chromogen (I) is 2,2''-azino-di-(3-ethyl-benzthiazolone-6-sulfonic acid) and said modifier is p-amino-salicylic acid.
Claim 15
Dependent Claim 39 words
Diagnostic agent according to claim 9 wherein said modifier is a member selected from the group consisting of o-amino-phenol-p-sulfonic acid, (1-amino-naphthol-8)-2, 4-disulfonic acid, (7-amino-naphthol-1)-3,6-disodium sulfonate, naphthyl-1-amino-6-sulfonic acid, naphthyl-1-amino-8-sulfonic acid, p-aminosalicylic acid, o-amino-phenol, m-amino-phenol, p-phenetidene, 2-hydroxy-4-amino-4-methoxy-diphenylamine, and Alpha -naphthol-2-sulfonic acid.
Claim 16
Dependent Claim 64 words
Process for the analytical determination of hydroperoxide, a substance which reacts with the liberation of hydroperoxide, peroxidase and a peroxidate-active substance which comprises contacting a liquid containing the substance of interest with a reagent comprising a diagnostic agent according to claim 1, producing a color with respect to said liquid as visual evidence of the presence of said substance of interest in said liquid.
Claim 17
Dependent Claim 64 words
Process for the analytical determination of hydroperoxide, a substance which reacts with the liberation of hydroperoxide, peroxidase and a peroxidate-active substance which comprises contacting a liquid containing the substance of interest with a reagent comprising a diagnostic agent according to claim 9, producing a color with respect to said liquid as visual evidence of the presence of said substance of interest in said liquid.

References Cited (Backward Citations)

US3183173A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1974-12-13 1975-06-14 1975-12-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1978-12-13 1979-06-14 1979-12-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1982-12-13 1983-06-14 1983-12-14 $7700.00 Window Closed / Lapsed

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