US3621005A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Ppd-s (tuberculin protein) combined with glucuronic acid and method for preparing the same
Assignee: ZAIDAN HOJIN TOKYO SEIKAGAKU
•
Filing: 1968-08-19
•
Granted: 1971-11-16
•
Expires: 1988-08-19
Abstract
Abstract Tuberculin protein (hereinafter referred to as ''''PPD-S'''' in such a sense as a purified protein derivative) combined with glucuronic acid has less side effect and is chemically stable. The PPD-S combined with glucuronic acid is prepared by treating PPD-S with glucuronic acid metal salt, such as sodium glucuronate or potassium glucuronate, or with glucuronolactone.
Inventors
- 👤 Morizo Ishidate
- 👤 Kenji Yusawa
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 05:42
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/02; A61K39/04; Y; Y10; Y10S; Y10S530/00; Y10S530/82; Y10S530/825
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
29 words
A method according to claim 1 including the steps of purifying the dialyzed mixture using a cross-linked dextran gel, again dialyzing the purified mixture and lyophilizing the thus-purified mixture.
Claim 2
Dependent Claim
19 words
A method according to claim 1 wherein the ratio of PPD-S to glucuronate or glucuronolactone is 1:2 to 1:5.
Claim 3
Dependent Claim
9 words
The product prepared by the method of claim 1.
References Cited (Backward Citations)
GB919782A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-11-15 | 1975-05-17 | 1975-11-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-11-15 | 1979-05-17 | 1979-11-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-11-15 | 1983-05-17 | 1983-11-16 | $7700.00 | Window Closed / Lapsed |