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US3620675A Expired / Lapsed US ⏱️ 0.0 years remaining

Apparatus for the measurement of dissolution rates

Assignee: Pharmacia and Upjohn Co
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Filing: 1969-02-10
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Granted: 1971-11-16
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Expires: 1989-02-10
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Abstract

Abstract An apparatus for the measurement of dissolution rates of solid materials such as tablets, capsules, modules, or the like, includes a dissolution fluid reservoir, pumping means for the fluid, a dissolution chamber adapted to receive a solid material to be dissolved and the dissolution fluid, and means for measuring the concentration of the dissolved solid in the effluent from the dissolution chamber.

Inventors

  • 👤 Carter L Olson

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 00:45
CPC Classifications
G; G01; G01N; G01N13/00; G01N2013/006; G01N35/00; G01N2035/00178; G01N2035/00188; G01N2035/00198; G01N33/00; G01N33/15

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 51 words
The apparatus in accordance with claim 1 wherein the dissolution chamber is an elongated, vertically disposed, cylindrical container having an opening at the bottom through which said fluid is admitted and an opening at the top through which said fluid containing dissolved said solid material is exited to the monitoring means.
Claim 2
Dependent Claim 48 words
The apparatus in accordance with claim 2 wherein the said means for retaining said solid material in said dissolution chamber comprises fluid-permeable, solids-retaining glass frits situated within the dissolution chamber in a spaced relationship to each other and adapted to receive therebetween a solid material to be dissolved.
Claim 3
Dependent Claim 48 words
The apparatus in accordance with claim 2 wherein the said means for retaining said solid material in said dissolution chamber comprises a fluid-permeable, solids-retaining glass frit situated within the dissolution chamber near the bottom opening and a fibrous plug situated within the dissolution chamber near the top opening.
Claim 4
Independent Claim 47 words
A method for ascertaining the rate of dissolution of a solid material in a particular fluid which comprises continuously moving said fluid at a known rate past said solid material and in contact therewith, and monitoring the resulting concentration of said solid material dissolved in said fluid.
Claim 5
Dependent Claim 25 words
The method in accordance with claim 5 wherein said fluid contains no dissolved solid material therein prior to the contact thereof with said solid material.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1974-11-15 1975-05-17 1975-11-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1978-11-15 1979-05-17 1979-11-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1982-11-15 1983-05-17 1983-11-16 $7700.00 Window Closed / Lapsed

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