Process for continuous preparation of amino-chloro-s-triazines

Abstract

Abstract A CONTINUOUS PROCESS FOR PRODUCING FIRST AN INTERMEDIATE 2,4-DICHLORO-6-LOWER ALKYLAMINO-S-TRIZINE AND THEN THEREFROM A 2-CHLORO-4,6-BIS LOWER ALKYLAMINO-S-TRIAZINE HERBICIDE. A FIRST REACTION MIXTURE IS ESTABLISHED AND MAINTAINED IN WHICH CYANURIC CHLORIDE IN ORGANIC SOLVENT SOLUTION IS REACTED IN A SUBSTANTIALLY NON-AQUEOUS MEDIUM WITH A LOWER ALKYLAMINE TO FORM A 2,4-DICHLORO-6-LOWER ALKYLAMINO-S-TRIAZINE AND HYDROCHLORIC ACID. AN ORGANIC SOLVENT SOLUTION OF CYANURIC CHLORIDE, AN AMINE TO BE REACTED THEREWITH, AND AN ACID ACCEPTOR ARE CONTINUOUSLY AND SIMULTANEOUSLY ADDED TO THE FIRST REACTION MIXTURE. AN ORGANIC SOLVENT SOLUTION OF A 2,4-DICHLORO-6-LOWER ALKYLAMINO-S-TRIAZINE IS CONTINUOUSLY WITHDRAWN FROM THE FIRST REACTION MIXTURE AND CONTINUOUSLY ADDED WITH A LOWER ALKYLAMINE AND AN ACID ACCEPTOR TO A SECOND REACTION MIXTURE. A SOLVENT SOLUTION OF A 2-CHLORO-4,6-BIS-LOWER ALKYLAMINO-S-TRIAZINE IS CONTINUOUSLY WITHDRAWN FROM THE SECOND REACTION MIXTURE AND THE LATTER DIAMINO COMPOUND IS RECOVERED FROM ITS SOLUTION. THE AMOUNT OF REACTANTS USED IS EQUIVALENT TO ABOUT ONE MOLE OF CYANURIC CHLORIDE, ONE MOLE OF AMINE AND ABOUT ONE MOLE OF ACID ACCEPTOR IN THE FIRST REACTION MIXTURE FOR EACH MOLE OF DICHLORO PRODUCT BEING WITHDRAWN FROM SAID FIRST REACTION MIXTURE, AND ABOUT ONE MOLE OF THE DICHLORO PRODUCT, ABOUT ONE MOLE OF AMINE AND ABOUT ONE MOLE OF ACID ACCEPTOR ARE ADDED TO THE SECOND REACTION MIXTURE FOR EACH MOLE OF DIAMINO REACTION PRODUCT BEING WITHDRAWN FROM THE SECOND REACTION MIXTURE. THE TEMPERATURE IN THE FIRST REACTION MIXTURE RANGES FROM ABOUT -10 TO 60*C. AND THE TEMPERATURE OF THE SECOND REACTION MIXTURE RANGES FROM ABOUT 20 TO 90*C. THE PH IS ABOUT 9-12.

Inventors

• 👤 John F Ferguson
• 👤 Philip G Mccracken

Bibliographic Details