US3585189A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Unsaturated nucleosides and processes for their preparation
Assignee: Roche Palo Alto LLC
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Filing: 1969-06-27
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Granted: 1971-06-15
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Expires: 1989-06-27
Abstract
Abstract 5''-DEOXY-B-D-ERYTHRO-PENT-4''-ENOFURANOSYL, 2'',5''-DIDEOXY-B-D-GLYCERO-PENT-4''-ENOFURANOSYL AND 6''-DEOXY-B-DERYTHRO-HEX-5''-ENOFURAN-2-ULOSYL NUCLEOSIDES ARE PREPARED BY DEHYDROHALOGENATING THE CORRESPONDING 5''-DEOXY-5''IODORIBOFURANOSYL, 2'',5''-DIDEOXY-5''-IODORIBOFURANOSYL AND 6''-DEOXY-6''-IODOPSICOFURANOSYL NUCLEOSIDES WITH 1,5-DIAZOBICYCLO-(4-3-0)-NON-5-ENE. THESE UNSATURATED NUCLEOSIDES ARE USEFUL IN PRODUCING METABOLIC DEFICIENCIES IN BIOLOGICAL SYSTEMS. THE IODO STARTING COMPOUNDS IN THE PURINE SERIES ARE PREPARED BY REACTING THE CORRESPONDING 5'' AND 6''-HYDROXY COMPOUNDS WITH ALKYLTRIARYLOXYPHOSPHONIUM IODIDE OR ARALKYLTRIARYLOXYPHOSPHONIUM IODIDE.
Inventors
- 👤 Julien P Verheyden
- 👤 John G Moffatt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 05:31
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/10; C07H19/16
Claims Analysis
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References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-06-14 | 1974-12-14 | 1975-06-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-06-14 | 1978-12-14 | 1979-06-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-06-14 | 1982-12-14 | 1983-06-15 | $7700.00 | Window Closed / Lapsed |