2-aryl- or aralkyl-substituted benzazole derivatives
Abstract
Abstract NEW COMPOUNDS HAVING THE GENERAL FORMULA 1,2-(-X-C(-Y-(R2,PHENYLENE)-O-(CH(-R4))N-CO-R3)=N-), R1-BENZENE WHEREIN R1 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND CHLORINE, R2 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND LOWER ALKOXY, R3 IS SELECTED FROM THE GROUP CONSISTING OF PIPERIDINO AND A-METHYL-BENZYLAMINO RADICALS, R4 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND METHYL RADICAL, X IS SELECTED FROM THE GROUP CONSISTING OF =O, =S, AND =NH, Y IS SELECTED FROM THE GROUP CONSISTING OF DIRECT BOND AND ALKYLENE HAVING FROM 1 TO 2 CARBON ATOMS, AND N IS SELECTED FROM THE GROUP CONSISTING OF 1 AND 2, AND THE POSITIONS OF R2 AND OF THE ETHER BOND IN THE PHENYL RADICAL ARE SELECTED FROM THE GROUP CONSISTING OF 2'', 3'', AND 4'', AND THEIR ACID ADDITION SALTS AND QUATERNARY AMMONIUM DERIVATIVES. THESE COMPOUNDS POSSESS VALUABLE PHARMACOLOGICAL PROPERTIES. THEY SHOW ANTI-ANGINOSE, CORONARY VASODILATOR AND PERIPHERAL CIRCULATION ENHANCING EFFECTS.
Inventors
- 👤 Kalman Hideg
- 👤 Laszlo Szekeres
- 👤 Gyula Popp
Bibliographic Details
Claims Analysis
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