N-aromatic substituted acid amides and esters
Abstract
Abstract N-AROMATIC SUBSTITUTED ACID AMIDE COMPOUNDS OF THE FORMULA ((R4,R5-PHENYL)-Y-C<(=CH-CH=CH-CH=X-)(-R3), (-NH-CO-CH(-R2)-Z-CH3) WHEREIN: Z IS -CO-, -CH(-OH)-, OR -CH(-O-ACYL)- WHEREIN THE ACYL IS THE ACYL GROUP OF A LOWER ALIPHATIC, PREFERABLY, ALKYL CARBOXYLIC ACID OR OF A MONOALIPHATIC PREFERABLY, ALKYL ESTER OF CARBONIC ACID, R2 IS H OR LOWER ALKYL, R3 IS H, HALOGEN, LOWER ALKYL OR LOWER ALKOXY, EACH OF R4 AND R5 TAKEN INDIVIDUALLY IS HYDROGEN, HALOGEN, LOWER ALKYL NITRO, TRIFLUOROMETHYL, LOWER ALKOXY, LOWER ALKYL AMINO, AMINO, HYDROXY, ACYL-OXY AS DEFINED ABOVE OR ACYL-AMINO AS DEFINED ABOVE, X IS =H-OR=CH-AND Y IS-CH2-OR-NHAND WHEREIN WHEN Z IS -CO- X IS CH AND Y IS NH AT LEAST ONE OR R2, R3, R4 AND R5 IS OTHER THAN HYDROGEN. SUCH COMPOUNDS HAVE VALUABLE PHARAMACEUTICAL PROPERTIES, SUCH AS, ANTI-INFLAMMATORY, ANALGESIC, ANTIPYRETIC AND/ OR ANTI-SPASMODIC PROPERTIES.
Inventors
- 👤 Kurt Thiele
Bibliographic Details
Claims Analysis
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