Certain pyridoyl and furoyl esters of 2-(lower alkyl) - 3 - (lower alkayl)-4-aryl-3 or 4-cyclohexene carbinols
Abstract
Abstract COMPOUNDS OF THE GENERAL FORMULA 1-(R''-COO-CH2-),2-R",3-R"'',4-(R-PHENYL)CYCLOHEX-3 OR 4-ENE ARE DISCLOSED WHEREIN-R IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, HYDROXY LOWER ALKOXY OF UP TO 8 CARBON ATOMS, LOWER ALKYL OF UP TO 8 CARBON ATOMS, AND LOWER ALKYL ANILINO OF UP TO 4 CARBON ATOMS; -R'' IS SELECTED FROM THE GROUP CONSISTING OF ALKYL AND ALKENYL OF UP TO 20 CARBON ATOMS, CYCLOALKYL LOWER ALKYL OF UP TO 3 CARBON ATOMS IN THE ALKYL PORTIONS, ADAMANTYL, PYRIDYL, FURYL, LOWER ALKYL CARBOXYLIC ACIDS AND THEIR ALKALI METAL SALTS, ESTERS AND CARBAMATES; AND R" AND R''" ARE SELECTED FROM THE GROUP CONSISTING OF LOWER ALKYL OF UP TO 3 CARBON ATOMS. THESE COMPOUNDS EXHIBITS ESTROGENIC PROPERTIES AND WHEN GIVEN IN A SINGLE SUBCUTANEOUS DOSE HAVE LONG ACTING EFFECTS IN THE SUPPRESSION OF ANIMAL REPRODUCTION.
Inventors
- 👤 George Karmas
Bibliographic Details
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