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US3552387A Expired / Lapsed US ⏱️ 0.0 years remaining

Combination syringe and vial

Assignee: Individual
•
Filing: 1968-07-16
•
Granted: 1971-01-05
•
Expires: 1988-07-16
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Abstract

Abstract The invention relates to a combination syringe and vial, each containing a separate chamber having an individual ingredient therein. The syringe and vial are assembled in interconnected relation to each other with the hub and cannula of the syringe extending within the vial in a manner to simultaneously support and seal the hub of the syringe with respect to a first closure in the vial and the distal portion of the cannula with respect to a second closure supported by the vial and in spaced-apart relation to the first closure, to maintain the respective chambers sealed off from each other. The first closure has a preformed axial bore extending entirely therethrough, and the second closure has a preformed axially extending channel therein. The dispensing of the ingredients occurs by displacing in a longitudinal direction the syringe and vial until the seal between the distal portion of the cannula and second closure is released, permitting movement of the plunger in the syringe to force the ingredient therein into the vial with resultant mixing of the two ingredients.

Inventors

  • 👤 Peter A Stevens

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 21:02
CPC Classifications
A; A61; A61J; A61J1/00; A61J1/14; A61J1/20; A61J1/2096; A61J1/2093; A61M; A61M5/00; A61M5/178; A61M5/31; A61M5/315; A61M5/31596; A61J1/2003; A61J1/2006; A61J1/201; A61J1/202; A61J1/2031; A61J1/2041

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 360 words
A device for both maintaining separately and thereafter mixing ingredients, comprising in combination: A. syringe means having a cannula extending therefrom and communicating with a storage chamber for containing an ingredient, said syringe means having plunger means in said storage chamber; B. vial means having a mixing chamber for containing an ingredient, and a first opening and a second opening in spacedapart relation, each communicating with said mixing chamber; C. supporting means comprising first and second closure means inserted respectively in said first and second openings and having a preformed axial bore extending entirely through said first closure means and a preformed axially extending channel in said second closure means communicating with said chamber and in coaxial alignment with said axial bore for receiving said syringe means and the proximate portion of the cannula in said axial bore and the distal portion of the cannula in the axially extending channel for mounting said syringe means on said vial means to provide support at spaced-apart positions for said syringe means and said cannula, with said cannula extending into and being supported in said mixing chamber, so as to releasably connect and firmly retain said syringe means and said cannula relative to said vial means; and D. said first and second closure means each having at least one portion thereof comprising sealing means for frictionally engaging said syringe means and said cannula distal portion in said mixing chamber, said sealing portion in said axial bore being of a diameter relative to the outer diameter of the syringe to provide sealing engagement therebetween, and said sealing portion in said axially extending channel being of a diameter relative to the outer diameter of said cannula to provide sealing engagement therebetween, such that said cannula distal portion is dislodged from said sealing means in said mixing chamber by longituDinally displacing said vial means and syringe means a preselected distance until said distal portion is removed from said sealing means, so as to permit said syringe ingredient to be discharged into said vial means and mixed with said vial ingredient, and the resultant fluent mixture can be withdrawn from said vial means into said syringe means.
Claim 2
Independent Claim 360 words
A device for both maintaining separately and thereafter mixing ingredients, comprising in combination: A. syringe means having a cannula extending therefrom and communicating with a storage chamber for containing an ingredient, said syringe means having plunger means in said storage chamber; B. vial means having a mixing chamber for containing an ingredient, and a first opening and a second opening in spacedapart relation, each communicating with said mixing chamber; C. supporting means comprising first and second closure means inserted respectively in said first and second openings and having a preformed axial bore extending entirely through said first closure means and a preformed axially extending channel in said second closure means communicating with said chamber and in coaxial alignment with said axial bore for receiving said syringe means and the proximate portion of the cannula in said axial bore and the distal portion of the cannula in the axially extending channel for mounting said syringe means on said vial means to provide support at spaced-apart positions for said syringe means and said cannula, with said cannula extending into and being supported in said mixing chamber, so as to releasably connect and firmly retain said syringe means and said cannula relative to said vial means; and D. said first and second closure means each having at least one portion thereof comprising sealing means for frictionally engaging said syringe means and said cannula distal portion in said mixing chamber, said sealing portion in said axial bore being of a diameter relative to the outer diameter of the syringe to provide sealing engagement therebetween, and said sealing portion in said axially extending channel being of a diameter relative to the outer diameter of said cannula to provide sealing engagement therebetween, such that said cannula distal portion is dislodged from said sealing means in said mixing chamber by longituDinally displacing said vial means and syringe means a preselected distance until said distal portion is removed from said sealing means, so as to permit said syringe ingredient to be discharged into said vial means and mixed with said vial ingredient, and the resultant fluent mixture can be withdrawn from said vial means into said syringe means.
Claim 3
Dependent Claim 78 words
A device according to claim 1, wherein the longitudinal length of said sealing means between said syringe means and said vial means is greater than the longitudinal length of said sealing means between the distal portion of said cannula and said vial means, so as to permit the withdrawal of said cannula from sealing engagement in said mixing chamber while said vial means remains in sealing engagement with said syringe means to maintain sterility in said mixing chamber.
Claim 4
Dependent Claim 77 words
A device according to claim 1, wherein the longitudinal length of said supporting means between said syringe means and said vial means is greater than the longitudinal length of said supporting means between the distal portion of said cannula and said vial means, so as to permit the withdrawal of said cannula from supporting engagement within said mixing chamber while said vial remains in supported relation with said syringe means to permit the mixture to be obtained.
Claim 5
Dependent Claim 26 words
A device according to claim 1, wherein said supporting means retains the distal portion of said cannula in a fixed position to prevent lateral movement thereof.
Claim 6
Dependent Claim 20 words
A device according to claim 4, wherein said distal portion is supported a length at least equal to .01 inches.
Claim 7
Dependent Claim 34 words
A device according to claim 1, wherein the total longitudinal length of said device is not increased more than 20 percent of said individual syringe means, so as to obtain a compact assembly thereof.
Claim 8
Dependent Claim 55 words
A device according to claim 1, wherein said second closure means is dimensioned with respect to said second opening in said vial means such that when positioned therein a radially inwardly directed force is applied to compress said sealing portion of said axially extending channel against said cannula to further maintain fluidtight sealing engagement therebetween.
Claim 9
Dependent Claim 23 words
A device according to claim 7, wherein the longitudinal length of said channel is at least equal to the diameter of said cannula.
Claim 10
Dependent Claim 55 words
A device according to claim 7, wherein said second closure means includes a body portion extending within said second opening and a radial flange integrally formed therewith and extending exteriorly of said vial and an overseal secured to said vial means and said radial flange said channel extending substantially the length of said body portion.
Claim 11
Dependent Claim 23 words
A device according to claim 1, wherein said second opening extends through said vial and said second closure means is sealingly inserted therein.
Claim 12
Dependent Claim 21 words
A device according to claim 1, further including overseals retaining said first and second closure means relative to said vial means.
Claim 13
Dependent Claim 25 words
A device according to claim 1, wherein said second opening terminates in said mixing chamber and forms a seat for retaining said second closure therein.
Claim 14
Dependent Claim 48 words
A device according to claim 1, wherein said first and second openings are of a circular configuration and said first opening is of a diameter equal to or greater than the diameter of said second opening to permit the displacement of said second closure through said first opening.
Claim 15
Dependent Claim 27 words
A device according to claim 1, wherein said channel terminates in an enlarged pocket contained in said second closure into which the tip of said cannula extends.
Claim 16
Independent Claim 440 words
A device for both maintaining separately and thereafter mixing ingredients, comprising in combination: A. syringe means having a cannula extending therefrom and communicating with a storage chamber for containing a sterile ingredient, said syringe means having plunger means in said storage chamber; B. vial means having a mixing chamber for containing a sterile ingredient with a first opening and a second opening in spaced-apart relaTion, each communicating with the mixing chamber; C. first closure means sealingly inserted in the first opening of said vial means; D. second closure means inserted in the second opening of said vial means and fixedly secured thereto; E. first supporting means integral with said first closure means in the form of a preformed axial bore extending entirely therethrough mounting said syringe means on said vial means so as to releasably connect and firmly hold said syringe means and the proximate end of the cannula with respect to said vial means, in said axial bore, with said cannula extending through said first closure means and into said mixing chamber; F. second supporting means integral with said second closure means in the form of a preformed axially extending channel extending therein and communicating with said mixing chamber, so as to releasably connect and firmly hold the distal portion of said cannula within said mixing chamber relative to said vial means, such that the resistance of said respective supporting means must be overcome before longitudinally displacing said vial means and syringe means; G. first sealing means integral with said first closure means for functioning as a seal by having at least a portion of said axial bore relative to the syringe means extending therethrough of a diameter to provide for frictionally engaging said syringe and sealing said mixing chamber from the atmosphere; and H. second sealing means integral with said second closure means and communicating with said mixing chamber for functioning as a seal by having at least a portion of said axially extending channel in said second closure means of a diameter relative to the outer diameter of said cannula for frictionally engaging said cannula distal portion in said mixing chamber, such that it is dislodged from said sealing means by longitudinally displacing said vial means and syringe means a preselected distance until said distal portion is removed from said sealing means, so as to permit said syringe ingredient to be discharged into said vial means and mixed with said vial ingredient, and the resultant fluent mixture can be withdrawn from said vial means into said syringe means after which said supporting means is released so that said syringe means can be used to inject said mixture.
Claim 17
Independent Claim 440 words
A device for both maintaining separately and thereafter mixing ingredients, comprising in combination: A. syringe means having a cannula extending therefrom and communicating with a storage chamber for containing a sterile ingredient, said syringe means having plunger means in said storage chamber; B. vial means having a mixing chamber for containing a sterile ingredient with a first opening and a second opening in spaced-apart relaTion, each communicating with the mixing chamber; C. first closure means sealingly inserted in the first opening of said vial means; D. second closure means inserted in the second opening of said vial means and fixedly secured thereto; E. first supporting means integral with said first closure means in the form of a preformed axial bore extending entirely therethrough mounting said syringe means on said vial means so as to releasably connect and firmly hold said syringe means and the proximate end of the cannula with respect to said vial means, in said axial bore, with said cannula extending through said first closure means and into said mixing chamber; F. second supporting means integral with said second closure means in the form of a preformed axially extending channel extending therein and communicating with said mixing chamber, so as to releasably connect and firmly hold the distal portion of said cannula within said mixing chamber relative to said vial means, such that the resistance of said respective supporting means must be overcome before longitudinally displacing said vial means and syringe means; G. first sealing means integral with said first closure means for functioning as a seal by having at least a portion of said axial bore relative to the syringe means extending therethrough of a diameter to provide for frictionally engaging said syringe and sealing said mixing chamber from the atmosphere; and H. second sealing means integral with said second closure means and communicating with said mixing chamber for functioning as a seal by having at least a portion of said axially extending channel in said second closure means of a diameter relative to the outer diameter of said cannula for frictionally engaging said cannula distal portion in said mixing chamber, such that it is dislodged from said sealing means by longitudinally displacing said vial means and syringe means a preselected distance until said distal portion is removed from said sealing means, so as to permit said syringe ingredient to be discharged into said vial means and mixed with said vial ingredient, and the resultant fluent mixture can be withdrawn from said vial means into said syringe means after which said supporting means is released so that said syringe means can be used to inject said mixture.
Claim 18
Dependent Claim 92 words
A device according to claim 15, wherein the longitudinal length of said first sealing means between said syringe means and said vial means in said first closure means is greater than the longitudinal length of said second sealing means between the distal portion of said cannula and said vial means in said second closure means, so as to permit the withdrawal of said cannula from sealing engagement with said second closure means while said vial means is simultaneously in sealing engagement with said syringe means to maintain sterility in said mixing chamber.
Claim 19
Dependent Claim 53 words
A device according to claim 16, wherein said second sealing means further includes said second closure means dimensioned with respect to said second opening in said vial such that when positioned therein a radially inwardly directed force is applied to compress said channel against said cannula to further maintain fluidtight sealing engagement therebetween.
Claim 20
Independent Claim 542 words
A device for both maintaining separately and thereafter mixing sterile ingredients and for injecting the mixture, comprising in combination: A. syringe means having a cannula extending therefrom and communicating with a storage chamber for containing a sterile ingredient, said syringe means having plunger means in said storage chamber; B. vial means having a mixing chamber for containing a sterile ingredient with first and second openings in spaced-apart relation, each communicating with the mixing chamber; C. first closure means sealingly inserted in the first opening of said vial; D. second closure means inserted in the second opening of said vial; E. first supporting means integral with said first closure Means in the form of a preformed axial bore extending entirely therethrough for mounting said syringe means and the proximate portion of said cannula on said vial means so as to releasably connect and firmly hold said syringe means and cannula with respect to said vial means in said axial bore with said cannula extending into said mixing chamber; F. second supporting means integral with said second closure means in the form of a preformed axially extending channel extending therein and communicating with said mixing chamber, so as to releasably connect and firmly hold the distal portion of said cannula within said mixing chamber relative to said vial means, such that the resistance of said respective supporting means must be overcome before longitudinally displacing said vial means and syringe means; G. first sealing means integral with said first closure means for functioning as a seal by having at least a portion of said axial bore relative to the syringe means extending therethrough of a diameter to provide for frictionally engaging said syringe and sealing said mixing chamber from the atmosphere; H. second sealing means integral with said second closure means and communicating with said mixing chamber for functioning as a seal by having at least a portion of said axially extending channel in said second closure means of a diameter relative to the outer diameter of said cannula for frictionally engaging said cannula distal portion in said mixing chamber and sealing said mixing chamber from said storage chamber, such that said cannula is dislodged from said closure means by longitudinally displacing said vial means and syringe means a preselected distance until said distal portion is removed from said second sealing means, so as to permit said syringe ingredient to be discharged into said vial means and mixed with said vial ingredient, and the resultant fluent mixture can be withdrawn from said vial means into said syringe means after which said first supporting means is released so that said syringe means can be used to inject said mixture; I. said first sealing means being greater in length than said second sealing means, so as to permit the withdrawal of said cannula distal portion from sealing engagement with said second closure means while said syringe simultaneously remains in sealing engagement with said vial means to maintain sterility in said mixing chamber; and J. said first supporting means being greater in length than said second supporting means, so as to retain said syringe means in supported position relative to said vial means by said second supporting means after said cannula is withdrawn from said first supporting means.
Claim 21
Independent Claim 542 words
A device for both maintaining separately and thereafter mixing sterile ingredients and for injecting the mixture, comprising in combination: A. syringe means having a cannula extending therefrom and communicating with a storage chamber for containing a sterile ingredient, said syringe means having plunger means in said storage chamber; B. vial means having a mixing chamber for containing a sterile ingredient with first and second openings in spaced-apart relation, each communicating with the mixing chamber; C. first closure means sealingly inserted in the first opening of said vial; D. second closure means inserted in the second opening of said vial; E. first supporting means integral with said first closure Means in the form of a preformed axial bore extending entirely therethrough for mounting said syringe means and the proximate portion of said cannula on said vial means so as to releasably connect and firmly hold said syringe means and cannula with respect to said vial means in said axial bore with said cannula extending into said mixing chamber; F. second supporting means integral with said second closure means in the form of a preformed axially extending channel extending therein and communicating with said mixing chamber, so as to releasably connect and firmly hold the distal portion of said cannula within said mixing chamber relative to said vial means, such that the resistance of said respective supporting means must be overcome before longitudinally displacing said vial means and syringe means; G. first sealing means integral with said first closure means for functioning as a seal by having at least a portion of said axial bore relative to the syringe means extending therethrough of a diameter to provide for frictionally engaging said syringe and sealing said mixing chamber from the atmosphere; H. second sealing means integral with said second closure means and communicating with said mixing chamber for functioning as a seal by having at least a portion of said axially extending channel in said second closure means of a diameter relative to the outer diameter of said cannula for frictionally engaging said cannula distal portion in said mixing chamber and sealing said mixing chamber from said storage chamber, such that said cannula is dislodged from said closure means by longitudinally displacing said vial means and syringe means a preselected distance until said distal portion is removed from said second sealing means, so as to permit said syringe ingredient to be discharged into said vial means and mixed with said vial ingredient, and the resultant fluent mixture can be withdrawn from said vial means into said syringe means after which said first supporting means is released so that said syringe means can be used to inject said mixture; I. said first sealing means being greater in length than said second sealing means, so as to permit the withdrawal of said cannula distal portion from sealing engagement with said second closure means while said syringe simultaneously remains in sealing engagement with said vial means to maintain sterility in said mixing chamber; and J. said first supporting means being greater in length than said second supporting means, so as to retain said syringe means in supported position relative to said vial means by said second supporting means after said cannula is withdrawn from said first supporting means.

References Cited (Backward Citations)

DE848081C Cited
DE1064691B Cited
FR1167766A Cited
US3330281A Cited
US3376866A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1974-01-04 1974-07-06 1975-01-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1978-01-04 1978-07-06 1979-01-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1982-01-04 1982-07-06 1983-01-05 $7700.00 Window Closed / Lapsed

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