Medicinal preparations having a protracted activity and method of making them

Claim 1

A GELATIN CAPSULE FILLED WITH A GIVEN GUANTITY OF MEDICAMENT, ONE-THIRD OF WHICH IS INTENDED TO BE RELEASED WITHIN ABOUT THIRTY MINUTES IN GASTRIC FLUID, A SECONE THIRD OF WHICH IS INTENDED TO BE RELEASED AFTER ABOUT TWO HOURS IN GASTRIC FLUID, AND THE REMAINDER OF WHICH IS INTENDED TO BE RELEASED AFTER ABOUT EIGHT HOURS IN INTESTIONAL FLUID, SAID QUANTIY OF MEDICAMENT BEING UNIFORMLY DISTRIBUTED IN A HOMOGENEOUS MIXTURE OF THREE EQUAL PARTS BY WEIGHT OF NEARLY ROUND PEARL DROPS BETWEEN 0.5 AND 3 MM. IN DIAMETER, EACH HAVING THE MEDICAMENT UNIFORMLY DISTRIBUTED THEREIN; ONE-THIRD OF SAID PEARL DROPS HAVING BEEN PRODUCED BY DISSOLVING ONE-THIRD OF THE MEDICAMETN IN POLYETHYLENE GLYCOL 6,000 TO FORM A SOLUTION, DROPPING OR SPRAYING SAID SOLUTION THROUGH VERY FINE NOZZLES INTO THE LIQUID PARAFFIN, REMOVING THE PARAFFIN BY FILTRATION, DEGREASING AND DRYING; ONE-THIRD OF THE PEARL DROPS HAVING BEEN PRODUCED BY SUSPENDING ONE-THIRD OF THE MEDICAMENT IN PARAFFINUM SOLIDUM, DROPPING OR SPRAYING THE RESULTING SUSPENSION THROUGH FINE NOZZLES INTO WATER, REMOVING THE WATER BY FILTRATION, AND DRYING; AND ONE-THIRD OF THE PEARL DROPS HAVING BEEN PRODUCED BY SUSPENDING ONE-THIRD OF THE DRUG IN CERA ALBA, DROPPING OR SPRAYING THE RESULTING SUSPENSION THROUGH FINE NOZZLES INTO A MIXTURE OF ETHYL ALCOHOL AND WATER, REMOVING THIS COLLECTING FLUID BY FILTRATION, AND DRYING.