US3341540A
Expired / Lapsed
US
⏱️ 0.0 years remaining
3-amino-6-halopyrazinonitriles and their syntheses
Assignee: Merck and Co Inc
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Filing: 1965-10-04
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Granted: 1967-09-12
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Expires: 1985-10-04
Abstract
No abstract record available.
Inventors
- 👤 Jr Edward J Cragoe
- 👤 James H Jones
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 08:54
CPC Classifications
C; C07; C07D; C07D241/00; C07D241/02; C07D241/10; C07D241/14; C07D241/24; C07D241/26
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
153 words
A PROCESS FOR PREPARING 3-AMINO-5-X-6-HALOPYRAZINONITRILES COMPRISING THE REACTION OF A 3-AMINO-5-X-6HALOPYRAZINAMIDE WITH DIMETHYLFORMAMIDE AND AN AGENT SELECTED FROM PHOSPHORYL CHLORIDE AND THIONYL CHLORIDE TO GIVE N,N-DIMETHYL-N''-(3-CYANO-5-HALO-6-X-2-PYRAZINYL) FORMAMIDINE WHICH IS HYDROLYZED WITH A STRONG ACID TO 3-AMINO-5-X-6-HALOPYRAZINONITRILE, WHEREIN IN EACH OF THE FOREGOING PRODUCTS X IS SELECTED FROM HYDROGEN, CHLORO, BROMO, LOWER ALKYL, LOWER ALKOXY, LOWER ALKYLTHIO, PHENYL, HALOPHENYL, LOWER ALKYL PHENYL, PHENYL-LOWER ALKOXY, PHENYL-LOWER ALKYLTHIO AND -NR1R2, WHEREIN EACH OF THE VARIABLE RADICALS R1 AND R2 IS SEPARATELY SELECTED FROM HYDROGEN, PHENYL, HALOPHENYL, AND LOWER ALKYL PHENYL, LOWER ALKYL, LOWER ALKENYL, HALO-LOWER ALKYL, HYDROXY-LOWER ALKYL, LOWER (ALKOXYALKYL), LOWER(CYCLOALKYALKYL) WHEREIN THE CYCLOALKYL MOIETY HAS 3 TO 6 NUCLEAR CARBONS, LOWER(DIALKYLAMINOALKYL), PHENYL-LOWER ALKYL, LOWER-(ALKYLPHENYLALKYL), HALOPHENYL-LOWER ALKYL, PYRIDYL-LOWER ALKYL, FURYL-LOWER ALKYL, LOWER CYCLOALKYL HAVING FROM 3 TO 6 NUCLEAR CARBON ATOMS, LOWER ALKOXY, AND WHEREIN R1 AND R2 ARE JOINED TOGETHER TO FORM WITH THE NITROGEN TO WHICH THEY ARE ATTACHED A RADICAL OF THE STRUCTURE
Claim 2
Dependent Claim
153 words
A PROCESS FOR PREPARING 3-AMINO-5-X-6-HALOPYRAZINONITRILES COMPRISING THE REACTION OF A 3-AMINO-5-X-6HALOPYRAZINAMIDE WITH DIMETHYLFORMAMIDE AND AN AGENT SELECTED FROM PHOSPHORYL CHLORIDE AND THIONYL CHLORIDE TO GIVE N,N-DIMETHYL-N''-(3-CYANO-5-HALO-6-X-2-PYRAZINYL) FORMAMIDINE WHICH IS HYDROLYZED WITH A STRONG ACID TO 3-AMINO-5-X-6-HALOPYRAZINONITRILE, WHEREIN IN EACH OF THE FOREGOING PRODUCTS X IS SELECTED FROM HYDROGEN, CHLORO, BROMO, LOWER ALKYL, LOWER ALKOXY, LOWER ALKYLTHIO, PHENYL, HALOPHENYL, LOWER ALKYL PHENYL, PHENYL-LOWER ALKOXY, PHENYL-LOWER ALKYLTHIO AND -NR1R2, WHEREIN EACH OF THE VARIABLE RADICALS R1 AND R2 IS SEPARATELY SELECTED FROM HYDROGEN, PHENYL, HALOPHENYL, AND LOWER ALKYL PHENYL, LOWER ALKYL, LOWER ALKENYL, HALO-LOWER ALKYL, HYDROXY-LOWER ALKYL, LOWER (ALKOXYALKYL), LOWER(CYCLOALKYALKYL) WHEREIN THE CYCLOALKYL MOIETY HAS 3 TO 6 NUCLEAR CARBONS, LOWER(DIALKYLAMINOALKYL), PHENYL-LOWER ALKYL, LOWER-(ALKYLPHENYLALKYL), HALOPHENYL-LOWER ALKYL, PYRIDYL-LOWER ALKYL, FURYL-LOWER ALKYL, LOWER CYCLOALKYL HAVING FROM 3 TO 6 NUCLEAR CARBON ATOMS, LOWER ALKOXY, AND WHEREIN R1 AND R2 ARE JOINED TOGETHER TO FORM WITH THE NITROGEN TO WHICH THEY ARE ATTACHED A RADICAL OF THE STRUCTURE
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1970-09-11 | 1971-03-13 | 1971-09-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1974-09-11 | 1975-03-13 | 1975-09-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1978-09-11 | 1979-03-13 | 1979-09-12 | $7700.00 | Window Closed / Lapsed |