US3332935A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Preparation of guanosine and intermediates therein
Assignee: Ajinomoto Co Inc
•
Filing: 1964-08-05
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Granted: 1967-07-25
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Expires: 1984-08-05
Abstract
No abstract record available.
Inventors
- 👤 Yamazaki Akihiro
- 👤 Meguro Takashi
- 👤 Kumashiro Izumi
- 👤 Takenishi Tadao
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 02:23
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/16; C07H19/052
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
88 words
A METHOD OF PREPARING GUANOSINE FROM 5-AMINO-4CARBAMOYL - 1 - (2'',3''-O-ISOPROPYLIDENE-B-D-RIBOFURANOSYL) IMIDAZOLE AS A STARTING MATERIAL WHICH COMPRISES: (A) HEATING SAID STARTING MATERIAL WITH AROYL ISOTHIOCYANATE, WHEREBY 4-CARBAMOYL-5-(N''AROYLTHIOCARBAMOYL) AMINO - 1 - (2'',3''-O-ISOPROPYLIDENE-B-D-RIBOFURANOSYL) IMIDAZOLE IS PRODUCED AS A FIRST INTERMEDIATE; (B) REACTING SAID INTERMEDIATE WITH A METHYLATING AGENT TO FORM 4-CARBAMOYL -5 - (N''-AROYL-S-METHYLISOTHIOCARBAMOYL) AMINO1-(2'',3'' -O-ISOPROPYLIDENE-B-D-RIBOFURANOSYL) IMIDAZOLE; (C) HEATING SAID IMIDAZOLE SECOND INTERMEDIATE TO TRANSFORM THE SAME INTO 2-N-AROYL-2'',3''-O-ISOPROYLIDENEGUANOSINE AS A THIRD INTERMEDIATE; AND (D) HYDROLYZING SAID OSINE AS A THIRD INTERMEDIATE; AND (D) HYDROLYZING SAID THIRD INTERMEDIATE.
Claim 2
Independent Claim
88 words
A METHOD OF PREPARING GUANOSINE FROM 5-AMINO-4CARBAMOYL - 1 - (2'',3''-O-ISOPROPYLIDENE-B-D-RIBOFURANOSYL) IMIDAZOLE AS A STARTING MATERIAL WHICH COMPRISES: (A) HEATING SAID STARTING MATERIAL WITH AROYL ISOTHIOCYANATE, WHEREBY 4-CARBAMOYL-5-(N''AROYLTHIOCARBAMOYL) AMINO - 1 - (2'',3''-O-ISOPROPYLIDENE-B-D-RIBOFURANOSYL) IMIDAZOLE IS PRODUCED AS A FIRST INTERMEDIATE; (B) REACTING SAID INTERMEDIATE WITH A METHYLATING AGENT TO FORM 4-CARBAMOYL -5 - (N''-AROYL-S-METHYLISOTHIOCARBAMOYL) AMINO1-(2'',3'' -O-ISOPROPYLIDENE-B-D-RIBOFURANOSYL) IMIDAZOLE; (C) HEATING SAID IMIDAZOLE SECOND INTERMEDIATE TO TRANSFORM THE SAME INTO 2-N-AROYL-2'',3''-O-ISOPROYLIDENEGUANOSINE AS A THIRD INTERMEDIATE; AND (D) HYDROLYZING SAID OSINE AS A THIRD INTERMEDIATE; AND (D) HYDROLYZING SAID THIRD INTERMEDIATE.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1970-07-24 | 1971-01-23 | 1971-07-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1974-07-24 | 1975-01-23 | 1975-07-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1978-07-24 | 1979-01-23 | 1979-07-25 | $7700.00 | Window Closed / Lapsed |