US3331736A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Modified laryngotracheitis vaccine
Assignee: Merck Sharp & Dohme LLC
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Filing: 1963-02-11
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Granted: 1967-07-18
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Expires: 1983-02-11
Abstract
No abstract record available.
Inventors
- 👤 Emil F Gelenczei
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 13:14
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/12; A61K39/245; A61K2039/51; A61K2039/525; A61K2039/5254; A61K2039/55; A61K2039/552; C; C12; C12N; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16311; C12N2710/16334; Y; Y10; Y10S; Y10S424/00; Y10S424/816
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
122 words
THE METHOD OF PRODUCING A MODIFIED, ANTIGENIC LARYNGOTRACHEITIS VACCINE WHICH CAN BE SAFELY ADMINISTERED TO FOWL THROUGH THE RESPIRATORY ROUTE, COMPRISING THE STEPS OF: (A) FORMING A PLURALITY OF TISSUE CULTURES OF MATERIAL SELECTED FROM THE GROUP CONSISTING OF EMBRYONIC POULTRY LIVER TISSUE CELLS AND EMBRYONIC POULTRY KIDNEY TISSUE CELLS, (B) SERIALLY PASSING A VIRULENT, INFECTIOUS LARYNGOTRACHEITIS VIRUS THROUGH SAID CULTURES FOR A PLURALITY OF PASSAGES WHILE MAINTAINING SAID CULTURES AT A TEMPERATURE OF ABOUT 30* TO 40*C FOR ABOUT 1 TO 3 DAYS FOR EACH OF SAID PASSAGES, AND (C) CONTINUING SAID SERICAL PASSAGES UNTIL THE RESULTING VIRUS-CONTAINING TISSUE CULTURE FLUID, WHEN TITERED IN EMBRYONATING CHICKEN EGGS BY THE CHORIO-ALLANTOIC MEMBRANE METHOD, PRODUCES PREDOMINANTLY ATYPICAL, SMALL, PIN-POINT SIZE, GRAYISH POCK-TYPE LESIONS.
Claim 2
Independent Claim
122 words
THE METHOD OF PRODUCING A MODIFIED, ANTIGENIC LARYNGOTRACHEITIS VACCINE WHICH CAN BE SAFELY ADMINISTERED TO FOWL THROUGH THE RESPIRATORY ROUTE, COMPRISING THE STEPS OF: (A) FORMING A PLURALITY OF TISSUE CULTURES OF MATERIAL SELECTED FROM THE GROUP CONSISTING OF EMBRYONIC POULTRY LIVER TISSUE CELLS AND EMBRYONIC POULTRY KIDNEY TISSUE CELLS, (B) SERIALLY PASSING A VIRULENT, INFECTIOUS LARYNGOTRACHEITIS VIRUS THROUGH SAID CULTURES FOR A PLURALITY OF PASSAGES WHILE MAINTAINING SAID CULTURES AT A TEMPERATURE OF ABOUT 30* TO 40*C FOR ABOUT 1 TO 3 DAYS FOR EACH OF SAID PASSAGES, AND (C) CONTINUING SAID SERICAL PASSAGES UNTIL THE RESULTING VIRUS-CONTAINING TISSUE CULTURE FLUID, WHEN TITERED IN EMBRYONATING CHICKEN EGGS BY THE CHORIO-ALLANTOIC MEMBRANE METHOD, PRODUCES PREDOMINANTLY ATYPICAL, SMALL, PIN-POINT SIZE, GRAYISH POCK-TYPE LESIONS.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1970-07-17 | 1971-01-16 | 1971-07-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1974-07-17 | 1975-01-16 | 1975-07-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1978-07-17 | 1979-01-16 | 1979-07-18 | $7700.00 | Window Closed / Lapsed |