Patent US5612052A successfully refreshed from Google Patents.
US3293146A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Composition for detecting guanase and process for diagnosing viral hepatitis therewith
Assignee: Bayer Corp
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Filing: 1964-03-25
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Granted: 1966-12-20
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Expires: 1984-03-25
Abstract
No abstract record available.
Inventors
- 👤 Free Alfred Henry
- 👤 Hue Allen Chuol
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 19:57
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/34; G; G01; G01N; G01N2333/00; G01N2333/90; G01N2333/914; G01N2333/978
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
121 words
A COMPOSITION FOR THE DETECTION OF THE ENZYME GUANASE IN FLUIDS WHICH COMPRISES A REACTION SYSTEM COMPRISING GUANINE, XANTHINE OXIDASE, AN AZIDE FOR INHIBITING THE FORMATION OF INTERFERING CATALASE-PEROXIDE COMPLEXES, A BUFFER FOR MAINTAINING THE REACTION SYSTEM AT A PH OF BETWEEN ABOUT 7.5 TO 8.5 DURING THE HYDROLYTIC DEAMINATION AND OXIDATION OF GUANINE WITH THE CONCOMITANT FORMATION OF PEROXIDES, AND A DETECTION SYSTEM COMPRISING A CHROMOGEN RESPONSIVE TO THE PRESENCE OF PEROXIDES, A CATALYST HAVING PEROXIDATIVE ACTIVITY IN THE PRESENCE OF THE AZIDE FOR CATALYZING THE COLOR PRODUCING REACTION RESULTING FROM CONTACT OF SAID CHROMOGEN WITH PEROXIDE, AND A BUFFER FOR MAINTAINING THE COMBINED REACTION SYSTEM AND DETECTION SYSTEM DURING COLOR DEVELOPMENT AT A PH OF BETWEEN 4.5 AND 5.5.
Claim 2
Dependent Claim
121 words
A COMPOSITION FOR THE DETECTION OF THE ENZYME GUANASE IN FLUIDS WHICH COMPRISES A REACTION SYSTEM COMPRISING GUANINE, XANTHINE OXIDASE, AN AZIDE FOR INHIBITING THE FORMATION OF INTERFERING CATALASE-PEROXIDE COMPLEXES, A BUFFER FOR MAINTAINING THE REACTION SYSTEM AT A PH OF BETWEEN ABOUT 7.5 TO 8.5 DURING THE HYDROLYTIC DEAMINATION AND OXIDATION OF GUANINE WITH THE CONCOMITANT FORMATION OF PEROXIDES, AND A DETECTION SYSTEM COMPRISING A CHROMOGEN RESPONSIVE TO THE PRESENCE OF PEROXIDES, A CATALYST HAVING PEROXIDATIVE ACTIVITY IN THE PRESENCE OF THE AZIDE FOR CATALYZING THE COLOR PRODUCING REACTION RESULTING FROM CONTACT OF SAID CHROMOGEN WITH PEROXIDE, AND A BUFFER FOR MAINTAINING THE COMBINED REACTION SYSTEM AND DETECTION SYSTEM DURING COLOR DEVELOPMENT AT A PH OF BETWEEN 4.5 AND 5.5.
Claim 3
Dependent Claim
69 words
A PROCESS FOR THE DIAGNOSIS OF VIRAL HEPATITIS COMPRISING CONTACTING BLOOD SERUM FROM AN INDIVIDUAL SUSPECTED OF HAVING VIRAL HEPATITIS WITH A GUANASE DETECTING COMPOSITION COMPRISING A GUANINE CONTAINING REACTION SYSTEM CAPABLE OF HYDROLYTIC DEAMINATION AND OXIDATIN WITH THE CONCOMITANT FORMATION OF HYDROEN PEROXIDE IN THE PRESENCE OF GUANASE AND A CHROMOGENIC DETECTION SYSTEM FOR DETECTING SAID HYDROGEN PEROXIDE AND THEREAFTER DIAGNOSING HEPATITIS IF A POSITIVE RESPONSE IS OBTAINED,
Claim 4
Dependent Claim
69 words
A PROCESS FOR THE DIAGNOSIS OF VIRAL HEPATITIS COMPRISING CONTACTING BLOOD SERUM FROM AN INDIVIDUAL SUSPECTED OF HAVING VIRAL HEPATITIS WITH A GUANASE DETECTING COMPOSITION COMPRISING A GUANINE CONTAINING REACTION SYSTEM CAPABLE OF HYDROLYTIC DEAMINATION AND OXIDATIN WITH THE CONCOMITANT FORMATION OF HYDROEN PEROXIDE IN THE PRESENCE OF GUANASE AND A CHROMOGENIC DETECTION SYSTEM FOR DETECTING SAID HYDROGEN PEROXIDE AND THEREAFTER DIAGNOSING HEPATITIS IF A POSITIVE RESPONSE IS OBTAINED,
References Cited (Backward Citations)
US3099605A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1969-12-19 | 1970-06-20 | 1970-12-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1973-12-19 | 1974-06-20 | 1974-12-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1977-12-19 | 1978-06-20 | 1978-12-20 | $7700.00 | Window Closed / Lapsed |