US3281406A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for the production of highly active isomers of hypertensin ii and its analogues
Assignee: BASF Corp
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Filing: 1963-06-05
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Granted: 1966-10-25
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Expires: 1983-06-05
Abstract
No abstract record available.
Inventors
- 👤 Schwyzer Robert
- 👤 Riniker Bernhard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 19:42
CPC Classifications
C; C07; C07K; C07K7/00; C07K7/04; C07K7/14
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
87 words
PROCESS FOR THE MANUFACTURE OF HIGHLY ACTIVE ISOMERS OF HYPERTENSIN II AND OF ITS ANALOGUES HAVING A HYPERTENSIVE ACTION, WHEREIN A MEMBER SELECTED FROM THE GROUP CONSISTING OF THE A-OCTAPEPTIDE OF THE FORMULA 1-A-ASPARAGYL-L-A-(AMINO-LOWER ALKYL)-AMINO-ACETYL - L - AAMINO-LOWER ALKYL-ACETYL - L - TYROSYL-L-A-AMINO-LOWER ALKYL-ACETYL-L-HISTIDYL-L-PROLYL-L-PHENYLALANINE AND THE CORRESPONDING L-A-ASPARAGINYL COMPOUND IS HEATED IN AN AQUEOUS SOLUTION AT AN APPROXIMATELY NEUTRAL PH AND THE RESULTING D:L-B-ASPARAGYL-L-A-(AMINO-LOWR ALKYL)AMINO-ACETYL-L-A-AMINO-LOWER ALKYL-ACETYL - L - TYROSYLL - A - AMINO-LOWER ALKYL-ACETYL-L-HISTIDYL-L-PROLYL-LPHENYLALANINE IS ISOLATED IN ADMIXTURE WITH AT MOST 20% OF THE A-ISOMER.
Claim 2
Dependent Claim
87 words
PROCESS FOR THE MANUFACTURE OF HIGHLY ACTIVE ISOMERS OF HYPERTENSIN II AND OF ITS ANALOGUES HAVING A HYPERTENSIVE ACTION, WHEREIN A MEMBER SELECTED FROM THE GROUP CONSISTING OF THE A-OCTAPEPTIDE OF THE FORMULA 1-A-ASPARAGYL-L-A-(AMINO-LOWER ALKYL)-AMINO-ACETYL - L - AAMINO-LOWER ALKYL-ACETYL - L - TYROSYL-L-A-AMINO-LOWER ALKYL-ACETYL-L-HISTIDYL-L-PROLYL-L-PHENYLALANINE AND THE CORRESPONDING L-A-ASPARAGINYL COMPOUND IS HEATED IN AN AQUEOUS SOLUTION AT AN APPROXIMATELY NEUTRAL PH AND THE RESULTING D:L-B-ASPARAGYL-L-A-(AMINO-LOWR ALKYL)AMINO-ACETYL-L-A-AMINO-LOWER ALKYL-ACETYL - L - TYROSYLL - A - AMINO-LOWER ALKYL-ACETYL-L-HISTIDYL-L-PROLYL-LPHENYLALANINE IS ISOLATED IN ADMIXTURE WITH AT MOST 20% OF THE A-ISOMER.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1969-10-24 | 1970-04-25 | 1970-10-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1973-10-24 | 1974-04-25 | 1974-10-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1977-10-24 | 1978-04-25 | 1978-10-25 | $7700.00 | Window Closed / Lapsed |