US3131191A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for the preparation of noraporphines
Assignee: Smith Kline & French Laboratories Ltd
•
Filing: 1962-08-08
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Granted: 1964-04-28
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Expires: 1982-08-08
Abstract
No abstract record available.
Inventors
- 👤 Douglas Bryce
- 👤 Jerry A Weisbach
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 09:51
CPC Classifications
C; C07; C07D; C07D221/00; C07D221/02; C07D221/04; C07D221/18
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
84 words
IN THE PROCESS FOR THE PREPARATION OF NORAPORPHINES WHEREIN A 1-(2''-NITROGENZYL)-3,4-DIHYDROISOQUINOLINE IS REDUCES TO A 1-(2''-AMINOBENZYL)-1,2,3,4-TETRAHYDROQUINOLINE AND SAID 1-(2''-AMINOBENZYL)-1,2,3,4-TETRAHYDROQUINOLINE IS CONVERTED INTO THE CORRESPONDING DIAZONIUM SALT, SAID DIAZONIUM SALT THEN BEING HEATED SO AS TO EFFECT CYCLIZATION, THE STEPS WHICH COMPRISE, (A) INTRODUCING PRIOR TO SAID REDUCTION AN N-BENZYL GROUP IN SAID 1-(2''-NITROBENZYL)-3,4-DIHYDROISOQUINOLINE BY TREATMENT WITH A BENZYL HALIDE IN A NONAQUEOUS INERT ORGANIC SOLVENT, AND (B) REMOVIG SAID N-BENZYL GROUP SUBSEQUENT TO SAID CYCLIZATION BY CATALYTIC HYDROGENATION WHEREIN SAID CATALYST IS PALLADIUM-ON-INERT CARRIER.
Claim 2
Dependent Claim
84 words
IN THE PROCESS FOR THE PREPARATION OF NORAPORPHINES WHEREIN A 1-(2''-NITROGENZYL)-3,4-DIHYDROISOQUINOLINE IS REDUCES TO A 1-(2''-AMINOBENZYL)-1,2,3,4-TETRAHYDROQUINOLINE AND SAID 1-(2''-AMINOBENZYL)-1,2,3,4-TETRAHYDROQUINOLINE IS CONVERTED INTO THE CORRESPONDING DIAZONIUM SALT, SAID DIAZONIUM SALT THEN BEING HEATED SO AS TO EFFECT CYCLIZATION, THE STEPS WHICH COMPRISE, (A) INTRODUCING PRIOR TO SAID REDUCTION AN N-BENZYL GROUP IN SAID 1-(2''-NITROBENZYL)-3,4-DIHYDROISOQUINOLINE BY TREATMENT WITH A BENZYL HALIDE IN A NONAQUEOUS INERT ORGANIC SOLVENT, AND (B) REMOVIG SAID N-BENZYL GROUP SUBSEQUENT TO SAID CYCLIZATION BY CATALYTIC HYDROGENATION WHEREIN SAID CATALYST IS PALLADIUM-ON-INERT CARRIER.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1967-04-28 | 1967-10-28 | 1968-04-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1971-04-28 | 1971-10-28 | 1972-04-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1975-04-28 | 1975-10-28 | 1976-04-28 | $7700.00 | Window Closed / Lapsed |