US3074930A
Expired / Lapsed
US
⏱️ 0.0 years remaining
6-mercaptopurine nucleosides and method of preparing them
Assignee: SmithKline Beecham Corp
•
Filing: 1959-01-05
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Granted: 1963-01-22
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Expires: 1979-01-05
Abstract
No abstract record available.
Inventors
- 👤 George H Hitchings
- 👤 Goodman Irving
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 12:23
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/16
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
89 words
THE METHOD OF PREPRING NUCLEOSIDES SELECTED FROM THE CLASS CONSISTING OF NUCLEOSIDES OF 6-MERCAPTOPURINE, 2-AMINO-6-MERCAPTOPURINE, PURINE-6-THIOGLYCOSIDE AND 2AMINOPURINE-6-THIOGLYCOSIDE WHICH COMPRISES CONVERTING A REAGENT OF THE CLASS CONSISTING OF INOSINE AND GUANOSINE TO ITS O-ACYL DERIVATIVE, REACTING THE ACYLATED NUCLEOSIDE WITH PHOSPHORUS OXYCHLORIDE IN THE PRESENCE OF A HYDROGEN HALIDE ACCEPTOR, SO AS TO FORM THE ACYLATED NUCLEOSIDE OF THE CORRESPONDING 6-CHLOROPURINE, REACTING THE LATTER WITH A REAGENT SELECTED FROM THE CLASS CONSISTING OF THIOUREA, THE ALKALI THIOHEXOSES AND THE SALTS OF ALIPHATIC THIOCARBOXYLIC ACIDS AND DEACYLATING THE PRODUCT WITH
Claim 2
Independent Claim
89 words
THE METHOD OF PREPRING NUCLEOSIDES SELECTED FROM THE CLASS CONSISTING OF NUCLEOSIDES OF 6-MERCAPTOPURINE, 2-AMINO-6-MERCAPTOPURINE, PURINE-6-THIOGLYCOSIDE AND 2AMINOPURINE-6-THIOGLYCOSIDE WHICH COMPRISES CONVERTING A REAGENT OF THE CLASS CONSISTING OF INOSINE AND GUANOSINE TO ITS O-ACYL DERIVATIVE, REACTING THE ACYLATED NUCLEOSIDE WITH PHOSPHORUS OXYCHLORIDE IN THE PRESENCE OF A HYDROGEN HALIDE ACCEPTOR, SO AS TO FORM THE ACYLATED NUCLEOSIDE OF THE CORRESPONDING 6-CHLOROPURINE, REACTING THE LATTER WITH A REAGENT SELECTED FROM THE CLASS CONSISTING OF THIOUREA, THE ALKALI THIOHEXOSES AND THE SALTS OF ALIPHATIC THIOCARBOXYLIC ACIDS AND DEACYLATING THE PRODUCT WITH
Claim 3
Dependent Claim
6 words
A COMPOUND REPRESENTED BY THE FORMULA:
Claim 4
Dependent Claim
6 words
A COMPOUND REPRESENTED BY THE FORMULA:
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1966-01-21 | 1966-07-23 | 1967-01-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1970-01-21 | 1970-07-23 | 1971-01-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1974-01-21 | 1974-07-23 | 1975-01-22 | $7700.00 | Window Closed / Lapsed |