US3033849A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Manufacture of vitamin b12
Assignee: Armour and Co
•
Filing: 1958-05-19
•
Granted: 1962-05-08
•
Expires: 1978-05-19
Abstract
No abstract record available.
Inventors
- 👤 Robert H Sifferd
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 11:31
CPC Classifications
C; C07; C07H; C07H23/00; B; B01; B01J; B01J47/00; B01J47/014; C12; C12P; C12P19/00; C12P19/26; C12P19/28; C12P19/42
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
139 words
IN A PROCESS FOR PURIFYING VITAMIN B12-ACTIVE SUBSTANCES, THE STEPS OF CONTACTING WITH A CARBOXYLIC ACID ION EXCHANGE RESIN AN AQUEOUS SOLUTION OF VITAMIN B12-ACTIVE SUBSTANCES AND CONTAMINANTS THEREOF CONTAINING AT LEAST A PORTION OF HYDROXYCOBALAMIN AND HAVING A PH OF LESS THAN 2.5 TO ADSORB AT LEAST A PORTION OF THE VITAMIN B12ACTIVE SUBSTANCES THEREON, CONTACTING THE RESULTING ADSORBATE WITH A DILUTE AQUEOUS SOLUTION OF SULFUROUS ACID HAVING A PH OF LESS THAN ABOUT 2.5 TO CONVERT AT LEAST A PORTION OF THE ADSORBED HYDROXYCOBALAMIN TO SULFITOCOBALAMIN, THEN CONTACTING THE ADSORBATE WITH A MIXTURE OF WATER AND ACETONE TO SELECTIVELY ELUTE AT LEAST A PORTION OF THE CONTAMINANT SUBSTANCES, AND THEREAFTER CONTACTING THE ADSORBATE WITH AN AQUEOUS SOLUTION HAVING A PH OF LESS THAN 2.5 AND CONTAINING A WATER-MISCIBLE POLAR ORGANIC SOLVENT TO ELUTE THE VITAMIN B12-ACTIVE SUBSTANCES.
Claim 2
Dependent Claim
139 words
IN A PROCESS FOR PURIFYING VITAMIN B12-ACTIVE SUBSTANCES, THE STEPS OF CONTACTING WITH A CARBOXYLIC ACID ION EXCHANGE RESIN AN AQUEOUS SOLUTION OF VITAMIN B12-ACTIVE SUBSTANCES AND CONTAMINANTS THEREOF CONTAINING AT LEAST A PORTION OF HYDROXYCOBALAMIN AND HAVING A PH OF LESS THAN 2.5 TO ADSORB AT LEAST A PORTION OF THE VITAMIN B12ACTIVE SUBSTANCES THEREON, CONTACTING THE RESULTING ADSORBATE WITH A DILUTE AQUEOUS SOLUTION OF SULFUROUS ACID HAVING A PH OF LESS THAN ABOUT 2.5 TO CONVERT AT LEAST A PORTION OF THE ADSORBED HYDROXYCOBALAMIN TO SULFITOCOBALAMIN, THEN CONTACTING THE ADSORBATE WITH A MIXTURE OF WATER AND ACETONE TO SELECTIVELY ELUTE AT LEAST A PORTION OF THE CONTAMINANT SUBSTANCES, AND THEREAFTER CONTACTING THE ADSORBATE WITH AN AQUEOUS SOLUTION HAVING A PH OF LESS THAN 2.5 AND CONTAINING A WATER-MISCIBLE POLAR ORGANIC SOLVENT TO ELUTE THE VITAMIN B12-ACTIVE SUBSTANCES.
References Cited (Backward Citations)
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US2721162A
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GB763608A
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US2702263A
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US2830933A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1965-05-07 | 1965-11-06 | 1966-05-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1969-05-07 | 1969-11-06 | 1970-05-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1973-05-07 | 1973-11-06 | 1974-05-08 | $7700.00 | Window Closed / Lapsed |