US2978444A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polypeptides and process of preparing same
Assignee: CIBA PHARM PROD Inc
•
Filing: 1957-08-29
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Granted: 1961-04-04
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Expires: 1977-08-29
Abstract
No abstract record available.
Inventors
- 👤 Schwyzer Robert
- 👤 Iselin Beat
- 👤 Kappeler Heini
- 👤 Rittel Werner
- 👤 Riniker Bernhard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 05:19
CPC Classifications
C; C07; C07K; C07K7/00; C07K7/04; C07K7/14
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
79 words
A PROCESS FOR THE PREPARATION OF OCTAPEPTIDES WHICH COMPRISES REACTING N-CARBOBENZYLOXY-L-ASPARAGINYL-NITROL-ARGINYL-L-VALYL-L-TYROSINE, THE PRESENCE OF 1-CYCLOHEXYL-3-MORPHLINYLETHYL CARBODIIMIDE, WITH AN L-ISOLEUCYL-L-HISTIDYL - L - PROPYL-L-PHENYLALANINE LOWER ALKYL ESTER, SPLITTING OFF WITH HYDROGEN IN THE PRESENCE OF A PALLADIUM CATALYST THE CARBOBENZYLOXY GROUP FROM THE ASPARAGINYL RESIDUE AND THE NITRO GROUP FROM THE ARGINYL RESIDUE OF THE RESULTING OCTAPEPTIDE ESTER OF HYDROLYZING THE ESTER GROUP OF SAID OCTAPEPTIDE ESTER BY MEANS OF CAUSTIC SODA SOLUTION TO YIELD L-ASPARAGINYL-L-ARGINYL-LVALYL-L-TYROSYL-L-ISOLEUCYL-L-HISTIDYL - L - PHENYLALANINE.
Claim 2
Dependent Claim
79 words
A PROCESS FOR THE PREPARATION OF OCTAPEPTIDES WHICH COMPRISES REACTING N-CARBOBENZYLOXY-L-ASPARAGINYL-NITROL-ARGINYL-L-VALYL-L-TYROSINE, THE PRESENCE OF 1-CYCLOHEXYL-3-MORPHLINYLETHYL CARBODIIMIDE, WITH AN L-ISOLEUCYL-L-HISTIDYL - L - PROPYL-L-PHENYLALANINE LOWER ALKYL ESTER, SPLITTING OFF WITH HYDROGEN IN THE PRESENCE OF A PALLADIUM CATALYST THE CARBOBENZYLOXY GROUP FROM THE ASPARAGINYL RESIDUE AND THE NITRO GROUP FROM THE ARGINYL RESIDUE OF THE RESULTING OCTAPEPTIDE ESTER OF HYDROLYZING THE ESTER GROUP OF SAID OCTAPEPTIDE ESTER BY MEANS OF CAUSTIC SODA SOLUTION TO YIELD L-ASPARAGINYL-L-ARGINYL-LVALYL-L-TYROSYL-L-ISOLEUCYL-L-HISTIDYL - L - PHENYLALANINE.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1964-04-03 | 1964-10-03 | 1965-04-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1968-04-03 | 1968-10-03 | 1969-04-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1972-04-03 | 1972-10-03 | 1973-04-04 | $7700.00 | Window Closed / Lapsed |