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US2965543A Expired / Lapsed US ⏱️ 0.0 years remaining

Alcohol detoxification of pertussis vaccines

Assignee: Merck and Co Inc
•
Filing: 1953-07-03
•
Granted: 1960-12-20
•
Expires: 1973-07-03
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Abstract

No abstract record available.

Inventors

  • 👤 Elizabeth H Thiele

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 18:45
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/02; A61K39/099; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/851

Claims Analysis

Total Claims: 2
Claim 1
Independent Claim 67 words
A PROCESS FOR THE DETOXIFICATION OF THE PERTUSSIS THERMOLABILE TOXIN IN A SOLUTION CONTAINING BOTH SAID TOXIN AND THE PROTECTIVE ANTIGEN OF H. PERTUSSIS, WHICH COMPRISES ITS CONTACT FOR FROM 10 MINUTES TO 48 HOURS WITH A MONOHYDRIC ALIPHATIC ALCOHOL HAVING FROM 2 TO 4 CARBON ATOMS IN ITS MOLECULE UNDER REFRIGERATED CONDITIONS ABOVE ITS FREEZING POINT, THE ALCOHOL CONCENTRATION BEING FROM 20 TO 80% BY VOLUME.
Claim 2
Dependent Claim 67 words
A PROCESS FOR THE DETOXIFICATION OF THE PERTUSSIS THERMOLABILE TOXIN IN A SOLUTION CONTAINING BOTH SAID TOXIN AND THE PROTECTIVE ANTIGEN OF H. PERTUSSIS, WHICH COMPRISES ITS CONTACT FOR FROM 10 MINUTES TO 48 HOURS WITH A MONOHYDRIC ALIPHATIC ALCOHOL HAVING FROM 2 TO 4 CARBON ATOMS IN ITS MOLECULE UNDER REFRIGERATED CONDITIONS ABOVE ITS FREEZING POINT, THE ALCOHOL CONCENTRATION BEING FROM 20 TO 80% BY VOLUME.

References Cited (Backward Citations)

GB527803A Cited
US2371002A Cited
US2405740A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1963-12-20 1964-06-20 1964-12-20 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1967-12-20 1968-06-20 1968-12-20 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1971-12-20 1972-06-20 1972-12-20 $7700.00 Window Closed / Lapsed

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