US2960439A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Urea-dextrose composition and method for reducing intracranial pressure
Assignee: Wisconsin Alumni Research Foundation
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Filing: 1957-03-18
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Granted: 1960-11-15
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Expires: 1977-03-18
Abstract
No abstract record available.
Inventors
- 👤 Javid Manucher
- 👤 Settlage Elizabeth
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 11:03
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K47/00; A61K47/06; A61K47/26
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
49 words
A COMPOSITION CONSISTING ESSENTIALLY OF STERILE UREA AND DEXTROSE, THE RATIO OF SAID INGREDIENTS WHEN DISSOLVED IN WATER BEING SUCH AS TO PROVIDE ABOUT A 5-10% W./V. SOLUTION OF DEXTROSE HAVING DISSOLVED THEREIN ABOUT 5-30% W./V. OF UREA, SAID AQUEOUS SOLUTION BEING ADAPTABLE FOR USE IN LOWERING INTRACRANIAL PRESSURE.
Claim 2
Dependent Claim
49 words
A COMPOSITION CONSISTING ESSENTIALLY OF STERILE UREA AND DEXTROSE, THE RATIO OF SAID INGREDIENTS WHEN DISSOLVED IN WATER BEING SUCH AS TO PROVIDE ABOUT A 5-10% W./V. SOLUTION OF DEXTROSE HAVING DISSOLVED THEREIN ABOUT 5-30% W./V. OF UREA, SAID AQUEOUS SOLUTION BEING ADAPTABLE FOR USE IN LOWERING INTRACRANIAL PRESSURE.
Claim 3
Independent Claim
112 words
THE METHOD OF REDUCING INTRACRANIAL PRESSURE BY INTRAVENOUS ADMINISTRATION OF ASTERILE AQUEOUS SOLUTION OF UREA AND DEXTROSE AND AVOIDING HEMOGLOBINURIA NORMALLY RESULTING FROM THE INTRAVENOUS ADMINISTRATION OF AQUEOUS SOLUTIONS OF UREA AND A SECONDARY RISE IN PRESSURE ASSOCIATED WITH THE INTRAVEMOUS ADMINISTRATION OF AQUEOUS SOLUTIONS OF DEXTROSE, WHICH CONSISTS ESSENTIALLY IN STERILIZING UREA, DISSOLVING THE STERILE UREA IN A STERILE AQUEOUS 5-10% W./V. DEXTROSE SOLUTION TO PROVIDE A STERILE UREA-DEXTROSE SOLUTION CONTAINING ABOUT 5-30% W./V. OF UREA, AND THEN REDUCING THE INTRACRANIAL PRESSURE BY THE INTRAVENOUS ADMINISTRATION OF THE RESULTING SOLUTION IN AN AMOUNT SUFFICIENT TO PROVIDE ABOUT 100 MG. TO 1500 MG. OF UREA PER KG. OF BODY WEIGHT OF PATIENT.
Claim 4
Independent Claim
112 words
THE METHOD OF REDUCING INTRACRANIAL PRESSURE BY INTRAVENOUS ADMINISTRATION OF ASTERILE AQUEOUS SOLUTION OF UREA AND DEXTROSE AND AVOIDING HEMOGLOBINURIA NORMALLY RESULTING FROM THE INTRAVENOUS ADMINISTRATION OF AQUEOUS SOLUTIONS OF UREA AND A SECONDARY RISE IN PRESSURE ASSOCIATED WITH THE INTRAVEMOUS ADMINISTRATION OF AQUEOUS SOLUTIONS OF DEXTROSE, WHICH CONSISTS ESSENTIALLY IN STERILIZING UREA, DISSOLVING THE STERILE UREA IN A STERILE AQUEOUS 5-10% W./V. DEXTROSE SOLUTION TO PROVIDE A STERILE UREA-DEXTROSE SOLUTION CONTAINING ABOUT 5-30% W./V. OF UREA, AND THEN REDUCING THE INTRACRANIAL PRESSURE BY THE INTRAVENOUS ADMINISTRATION OF THE RESULTING SOLUTION IN AN AMOUNT SUFFICIENT TO PROVIDE ABOUT 100 MG. TO 1500 MG. OF UREA PER KG. OF BODY WEIGHT OF PATIENT.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1963-11-15 | 1964-05-16 | 1964-11-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1967-11-15 | 1968-05-16 | 1968-11-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1971-11-15 | 1972-05-16 | 1972-11-15 | $7700.00 | Window Closed / Lapsed |