US2850428A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Partially depolymerized hyaluronic acid as a spreading and lipemiaclearing agent
Assignee: Wyeth LLC
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Filing: 1954-08-18
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Granted: 1958-09-02
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Expires: 1974-08-18
Abstract
No abstract record available.
Inventors
- 👤 Seifter Joseph
- 👤 Baeder David Harry
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 06:22
CPC Classifications
C; C12; C12N; C12N9/00; C12N9/88
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
94 words
THE METHOD OF TREATING HYALURONIC ACID WHICH ESSENTIALLY COMPRISES: PREPARING A 5 PERCENT SOLUTION OF A HYALURONATE IN PHYSIOLOGICAL SALT SOLUTION, ADDING HYALURONIDASE IN A RATIO OF 20 TRU PER MILLIGRAM OF HYALURONATE, INCUBATING THE MIXTURE AT 38*C., TERMINATING THE HYALURONIDASE ACTION AFTER A PERIOD IN THE RANGE OF 5 TO LESS THAN ABOUT 60 MINUTES BY HEATING THE MIXTURE TO A HYALURONIDASE-REACTIVATING TEMPERATURE, THEREBY SIMULTANEOUSLY PRECIPITATING THE DEACTIVATED HYALURONIDASE, AND SEPARATING THE LATTER FROM THE SOLUTION, WHEREBY A SOLUTION IS OBTAINED OF PARTIALLY DEPOLYMERIZED HYALURONIC ACID IN PHYSIOLOGICAL SALT SOLUTION FREE OF HYALURONIDASE.
Claim 2
Independent Claim
94 words
THE METHOD OF TREATING HYALURONIC ACID WHICH ESSENTIALLY COMPRISES: PREPARING A 5 PERCENT SOLUTION OF A HYALURONATE IN PHYSIOLOGICAL SALT SOLUTION, ADDING HYALURONIDASE IN A RATIO OF 20 TRU PER MILLIGRAM OF HYALURONATE, INCUBATING THE MIXTURE AT 38*C., TERMINATING THE HYALURONIDASE ACTION AFTER A PERIOD IN THE RANGE OF 5 TO LESS THAN ABOUT 60 MINUTES BY HEATING THE MIXTURE TO A HYALURONIDASE-REACTIVATING TEMPERATURE, THEREBY SIMULTANEOUSLY PRECIPITATING THE DEACTIVATED HYALURONIDASE, AND SEPARATING THE LATTER FROM THE SOLUTION, WHEREBY A SOLUTION IS OBTAINED OF PARTIALLY DEPOLYMERIZED HYALURONIC ACID IN PHYSIOLOGICAL SALT SOLUTION FREE OF HYALURONIDASE.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1961-09-01 | 1962-03-03 | 1962-09-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1965-09-01 | 1966-03-03 | 1966-09-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1969-09-01 | 1970-03-03 | 1970-09-02 | $7700.00 | Window Closed / Lapsed |