US2849370A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Injectable insulin preparations with protracted effect and process of producing same
Assignee: Novo Terapeutisk Laboratorium AS
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Filing: 1954-05-28
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Granted: 1958-08-26
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Expires: 1974-05-28
Abstract
No abstract record available.
Inventors
- 👤 Petersen Karl
- 👤 Schlichtkrull Jorgen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 02:47
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/22; A61K38/28
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
102 words
AN INJECTABLE INSULIN PREPARATION WITH PROTRACTED EFFECT, COMPRISING A STERILE SUSPENSION OF AMORPHOUS ZINC PROTAMINE INSULIN IN AN AQUEOUS SUSPENSION MEDIUM HAVING A PH-VALUE BETWEEN 6 AND 8, SAID SUSPENSION CONTAINING PROTAMINE IN AN AMOUNT OF AT LEAST ONE MG. PER 1000 INTERNATIONAL UNITS OF INSULIN BUT NOT EXCEEDING THE AMOUNT NECESSARY FOR SUBSTANTIALLY COMPLETE PRECIPITATION OF THE INSULIN, AND ZINC IN AN AMOUNT BETWEEN 1/4 AND 20 MGS. PER 1000 INTERNATIONAL UNITS OF INSULIN, SAID SUSPENSION BEING ALSO FREE FROM PHOSPHATE AND CITRATE IONS IN AMOUNTS PREVENTING THE SUPPRESSION BY THE ZINC OF THE SOLUBILITY OF THE INSULIN AT PH 7.
Claim 2
Dependent Claim
102 words
AN INJECTABLE INSULIN PREPARATION WITH PROTRACTED EFFECT, COMPRISING A STERILE SUSPENSION OF AMORPHOUS ZINC PROTAMINE INSULIN IN AN AQUEOUS SUSPENSION MEDIUM HAVING A PH-VALUE BETWEEN 6 AND 8, SAID SUSPENSION CONTAINING PROTAMINE IN AN AMOUNT OF AT LEAST ONE MG. PER 1000 INTERNATIONAL UNITS OF INSULIN BUT NOT EXCEEDING THE AMOUNT NECESSARY FOR SUBSTANTIALLY COMPLETE PRECIPITATION OF THE INSULIN, AND ZINC IN AN AMOUNT BETWEEN 1/4 AND 20 MGS. PER 1000 INTERNATIONAL UNITS OF INSULIN, SAID SUSPENSION BEING ALSO FREE FROM PHOSPHATE AND CITRATE IONS IN AMOUNTS PREVENTING THE SUPPRESSION BY THE ZINC OF THE SOLUBILITY OF THE INSULIN AT PH 7.
References Cited (Backward Citations)
US2232641A
Cited
US2538018A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1961-08-25 | 1962-02-24 | 1962-08-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1965-08-25 | 1966-02-24 | 1966-08-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1969-08-25 | 1970-02-24 | 1970-08-26 | $7700.00 | Window Closed / Lapsed |