US2837516A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Delta 5, 16-3-ethylenedioxy-pregnadiene-11, 20-dione and process therefor
Assignee: Merck and Co Inc
•
Filing: 1953-09-09
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Granted: 1958-06-03
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Expires: 1973-09-09
Abstract
No abstract record available.
Inventors
- 👤 Lewis H Sarett
- 👤 George I Poos
- 👤 William F Johns
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 09:39
CPC Classifications
C; C07; C07D; C07D317/00; C07D317/08; C07D317/72; C07J; C07J5/00; C07J75/00; C07C; C07C2603/00; C07C2603/02; C07C2603/04; C07C2603/22; C07C2603/26
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
91 words
THE PROCESS WHICH COMPRISES INTIMATELY CONTACTING 2,4B-DIMETHYL-1-(BHYDROXYETHYL)-2-METHALLYL-7-ETHYLENEDIOXY -1,2,3,4,4A,4B,5,6,7,8,10,10A - DODECAHYDROHENANTHRENE-4-OL WITH PYRIDINE-CHROMIUM TRIOXIDE COMPLEX TO PRODUCE 2,4B - DIMETHYL - 1 -ACETALDEHYDRO - 2 - METHALLYL7 - ETHYLEMEDIOXY - 1,2,3,4,4A,4B,5,6,7,8,10,10A - DODECAHYDRPJENANTHRENE-4-ONE, REACTING THIS COMPOUND WITH OSMIUM TETROXIDE AND DECOMPOSING THE RESULTING OSMATE ESTER TO OBTAIN 2,4-DIMETHYL-1-ACETALDEHYDO-2-(B,Y-DIHYDOXYISOBUTYL) - 7 - ETHYLENEDIOXY - 1,2,3,4,4A,4B,5,6,7,1,10,10A-DODECAHYDROPHENANTHRENE-4-ONE, CLEAVING THIS COMPOUND BY REACTION WITH PERIODIC ACID TO PRODUCE 2,4BDIMETHYL - 1- ACETALDEHYDO-2-(B-KETOPROPYL)-7-ETHYLENEDIOXY - 1,2,3,4,4A,4B,5,6,7,8,10,10A - DODECAHYDROPHENANTHRENE-4-ONE, REACTING THIS COMPOUND WITH POTASSIUM HYDROXIDE TO PRODUCE 5,16-3-ETHYLNEDIOXY-PREGGNADIENE11,20-DIONE, AND HYDROLYZING THIS PRODUCT BY HEATING WITH ACID TO OBTAIN 4,16-PREGNADIENE-3,11,20-TRIONE.
Claim 2
Dependent Claim
91 words
THE PROCESS WHICH COMPRISES INTIMATELY CONTACTING 2,4B-DIMETHYL-1-(BHYDROXYETHYL)-2-METHALLYL-7-ETHYLENEDIOXY -1,2,3,4,4A,4B,5,6,7,8,10,10A - DODECAHYDROHENANTHRENE-4-OL WITH PYRIDINE-CHROMIUM TRIOXIDE COMPLEX TO PRODUCE 2,4B - DIMETHYL - 1 -ACETALDEHYDRO - 2 - METHALLYL7 - ETHYLEMEDIOXY - 1,2,3,4,4A,4B,5,6,7,8,10,10A - DODECAHYDRPJENANTHRENE-4-ONE, REACTING THIS COMPOUND WITH OSMIUM TETROXIDE AND DECOMPOSING THE RESULTING OSMATE ESTER TO OBTAIN 2,4-DIMETHYL-1-ACETALDEHYDO-2-(B,Y-DIHYDOXYISOBUTYL) - 7 - ETHYLENEDIOXY - 1,2,3,4,4A,4B,5,6,7,1,10,10A-DODECAHYDROPHENANTHRENE-4-ONE, CLEAVING THIS COMPOUND BY REACTION WITH PERIODIC ACID TO PRODUCE 2,4BDIMETHYL - 1- ACETALDEHYDO-2-(B-KETOPROPYL)-7-ETHYLENEDIOXY - 1,2,3,4,4A,4B,5,6,7,8,10,10A - DODECAHYDROPHENANTHRENE-4-ONE, REACTING THIS COMPOUND WITH POTASSIUM HYDROXIDE TO PRODUCE 5,16-3-ETHYLNEDIOXY-PREGGNADIENE11,20-DIONE, AND HYDROLYZING THIS PRODUCT BY HEATING WITH ACID TO OBTAIN 4,16-PREGNADIENE-3,11,20-TRIONE.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1961-06-02 | 1961-12-02 | 1962-06-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1965-06-02 | 1965-12-02 | 1966-06-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1969-06-02 | 1969-12-02 | 1970-06-03 | $7700.00 | Window Closed / Lapsed |