US2807569A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Adrenocorticotropic hormone composition
Assignee: Organon NV
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Filing: 1954-01-12
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Granted: 1957-09-24
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Expires: 1974-01-12
Abstract
No abstract record available.
Inventors
- 👤 Homan Jan Daniel Herman
- 👤 Neutelings Jacobus Pe Josephus
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:46
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/33; A61K38/35
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
125 words
AN INJECTABLE ADRENOCORTICOTROPIC HORMONE PREPARATION COMPRISING A SPARINGLY SOLUBLE ADRENOCORTICOTROPIC HORMONE-ZINC PHOSPHATE COMPLEX COMPOUND, TRISODIUM PHOSPHATE, SODIUM HYDROXIDE AND AN AQUEOUS INJECTABLE VEHICLE, SAID COMPLEX COMPOUND BEING SUSPENDED IN SAID VEHICLE IN FINELY DIVIDED FORM, SAID TRISODIUM PHOSPHATE BEING DISSOLVED THEREIN, THE PH OF SAID PREPARATION, ON BETWEEN ABOUT 6.0 AND ABOUT 8.0, SAID PREPARATION, ON INJECTION, PRODUCING A CONSIDERABLY PROLONGED AND HIGHER HORMONAL ACTIVITY THAN PRODUCED ON INJECTING AN EQUAL AMOUNT OF THE ADRENOCORTICOTROPIC HORMONE ITSELF IN AQUEOUS SOLUTION, THE ZINC CONTENT OF SAID PREPARATION BEING BETWEEN ABOUT 5 MG. AND ABOUT 15 MG. PER 100 U.S.P. UNITS OF SAID HORMONE, SAID AQUEOUS VEHICLE CONTAINING ABOUT 0.25-0.5% OF PHENOL AS PRESERVATIVE AGENT AND ABOUT 2.0-2.5% OF GLYCEROL AND BEING SUBSTANTIALLY ISOTONIC TO BLOOD SERUM.
Claim 2
Dependent Claim
125 words
AN INJECTABLE ADRENOCORTICOTROPIC HORMONE PREPARATION COMPRISING A SPARINGLY SOLUBLE ADRENOCORTICOTROPIC HORMONE-ZINC PHOSPHATE COMPLEX COMPOUND, TRISODIUM PHOSPHATE, SODIUM HYDROXIDE AND AN AQUEOUS INJECTABLE VEHICLE, SAID COMPLEX COMPOUND BEING SUSPENDED IN SAID VEHICLE IN FINELY DIVIDED FORM, SAID TRISODIUM PHOSPHATE BEING DISSOLVED THEREIN, THE PH OF SAID PREPARATION, ON BETWEEN ABOUT 6.0 AND ABOUT 8.0, SAID PREPARATION, ON INJECTION, PRODUCING A CONSIDERABLY PROLONGED AND HIGHER HORMONAL ACTIVITY THAN PRODUCED ON INJECTING AN EQUAL AMOUNT OF THE ADRENOCORTICOTROPIC HORMONE ITSELF IN AQUEOUS SOLUTION, THE ZINC CONTENT OF SAID PREPARATION BEING BETWEEN ABOUT 5 MG. AND ABOUT 15 MG. PER 100 U.S.P. UNITS OF SAID HORMONE, SAID AQUEOUS VEHICLE CONTAINING ABOUT 0.25-0.5% OF PHENOL AS PRESERVATIVE AGENT AND ABOUT 2.0-2.5% OF GLYCEROL AND BEING SUBSTANTIALLY ISOTONIC TO BLOOD SERUM.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1960-09-23 | 1961-03-25 | 1961-09-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1964-09-23 | 1965-03-25 | 1965-09-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1968-09-23 | 1969-03-25 | 1969-09-24 | $7700.00 | Window Closed / Lapsed |