US2666067A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Simultaneous oxidation and halogenation of steroids
Assignee: Pharmacia and Upjohn Co
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Filing: 1951-10-03
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Granted: 1954-01-12
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Expires: 1971-10-03
Abstract
No abstract record available.
Inventors
- 👤 Arthur R Hanze
- 👤 Robert H Levin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 22:14
CPC Classifications
C; C07; C07J; C07J5/00; C07J75/00
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
153 words
A PROCESS FOR THE CONCURRENT OXIDATION AND HALOGENATION OF A 21 - ACYLOXY - 3,17 - DIHYDROXYPREGNANE - 11.20 - DIONE TO A 4 - HALO - 21ACYLOXY - 17 - HYDROXYPREGNANE - 3,11,20 - TRIONE, WHICH COMPRISES: MIXING (A) A REAGENT SELECTED FROM THE GROUP CONSISTING OF N-BROMOACETAMIDE, N - BROMOSUCCINIMIDE, N - CHLOROSUCCINIMIDE, 3BROMO - 5,5 - DIMETHYLHYDANTOIN, 1.3 - DIBROMO5,5 - DIMETHYLHYDANTOIN, AND (B) A 21 - ACYLOXY3,17 - DIHYDROXYPREGNANE - 11,20 - DIONE, WHEREIN THE ACYLOXY GROUP CONTAINS UP TO AND INCLUDING WIGHT CARBON ATOMS, IN AN ORGANIC SOLVENT WHICH IS NOT SUBJECT TO OXIDATION OR HALOGENATION UNDER THE CONDITIONS OF THE REACTION TO CAUSE CONVERSION OF THE THREE-HYDROXY GROUP OF THE STEROID NUCLEUS TO A THREE-KETO GROUP AND TO CAUSE HALOGENATION AT CARBON ATOM FOUR OF THE STEROID NUCLEUS, AND SEPARATING THE 4 - HALO - 21 ACYLOXY - 17 - HYDROXY - PREGNANE - 3,11,20TRIONE THUS PRODUCED.
Claim 2
Dependent Claim
153 words
A PROCESS FOR THE CONCURRENT OXIDATION AND HALOGENATION OF A 21 - ACYLOXY - 3,17 - DIHYDROXYPREGNANE - 11.20 - DIONE TO A 4 - HALO - 21ACYLOXY - 17 - HYDROXYPREGNANE - 3,11,20 - TRIONE, WHICH COMPRISES: MIXING (A) A REAGENT SELECTED FROM THE GROUP CONSISTING OF N-BROMOACETAMIDE, N - BROMOSUCCINIMIDE, N - CHLOROSUCCINIMIDE, 3BROMO - 5,5 - DIMETHYLHYDANTOIN, 1.3 - DIBROMO5,5 - DIMETHYLHYDANTOIN, AND (B) A 21 - ACYLOXY3,17 - DIHYDROXYPREGNANE - 11,20 - DIONE, WHEREIN THE ACYLOXY GROUP CONTAINS UP TO AND INCLUDING WIGHT CARBON ATOMS, IN AN ORGANIC SOLVENT WHICH IS NOT SUBJECT TO OXIDATION OR HALOGENATION UNDER THE CONDITIONS OF THE REACTION TO CAUSE CONVERSION OF THE THREE-HYDROXY GROUP OF THE STEROID NUCLEUS TO A THREE-KETO GROUP AND TO CAUSE HALOGENATION AT CARBON ATOM FOUR OF THE STEROID NUCLEUS, AND SEPARATING THE 4 - HALO - 21 ACYLOXY - 17 - HYDROXY - PREGNANE - 3,11,20TRIONE THUS PRODUCED.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1957-01-11 | 1957-07-13 | 1958-01-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1961-01-11 | 1961-07-13 | 1962-01-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1965-01-11 | 1965-07-13 | 1966-01-12 | $7700.00 | Window Closed / Lapsed |