US2602045A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Azeotropic distillation process for preparing pure, crystalline penicillin salts
Assignee: Commercial Solvents Corp
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Filing: 1946-08-03
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Granted: 1952-07-01
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Expires: 1966-08-03
Abstract
No abstract record available.
Inventors
- 👤 Edward B Hodge
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 16:00
CPC Classifications
C; C07; C07D; C07D499/00; C07D499/04; C07D499/18
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
124 words
IN THE RECOVERY OF CRYSTALLINE ALKALI METAL PENICILLIN SALTS FROM PARTIALLY PURIFIED CONCENTRATED AQUEOUS SOLUTIONS THEREOF, THE PROCESS WHICH CONSISTS SUBSTANTIALLY IN MIXING SUCH AN AQUEOUS SOLUTION WITH A LOWER ALIPHATIC ALCOHOL HAVING FROM 2 TO 8 CARBON ATOMS AND WHICH FORMS AN AZEOTROPE WITH WATER, THE QUANTITY OF ALCOHOL ADDED BEING PRECIPITATION LESS THAN THAT REQUIRED TO CAUSE PRECIPITATION OF THE PENICILLIN BUT SUFFICIENT, UPON AZEOTROPIC DISTILLATION OF THE MIXTURE, SUBSTANTIALLY TO ELIMINATE THE WATER AND TO LEAVE A SUBSTANTIALLY SATURATED ALCOHOL SOLUTION OF THE PENICILLIN SALTS, AZEOTROPICALLY DISTILLING OFF THE WATER FROM THE MIXTURE UNDER A REDUCED PRESSURE AND AT A TEMPERATURE NOT SUBSTANTIALLY EXCEEDING 40* C., AND RECOVERING THE RESULTING CRYSTALS OF ALKALI METAL PENICILLIN FROM THE RESULTING SATURATED SOLUTION THEREOF.
Claim 2
Dependent Claim
124 words
IN THE RECOVERY OF CRYSTALLINE ALKALI METAL PENICILLIN SALTS FROM PARTIALLY PURIFIED CONCENTRATED AQUEOUS SOLUTIONS THEREOF, THE PROCESS WHICH CONSISTS SUBSTANTIALLY IN MIXING SUCH AN AQUEOUS SOLUTION WITH A LOWER ALIPHATIC ALCOHOL HAVING FROM 2 TO 8 CARBON ATOMS AND WHICH FORMS AN AZEOTROPE WITH WATER, THE QUANTITY OF ALCOHOL ADDED BEING PRECIPITATION LESS THAN THAT REQUIRED TO CAUSE PRECIPITATION OF THE PENICILLIN BUT SUFFICIENT, UPON AZEOTROPIC DISTILLATION OF THE MIXTURE, SUBSTANTIALLY TO ELIMINATE THE WATER AND TO LEAVE A SUBSTANTIALLY SATURATED ALCOHOL SOLUTION OF THE PENICILLIN SALTS, AZEOTROPICALLY DISTILLING OFF THE WATER FROM THE MIXTURE UNDER A REDUCED PRESSURE AND AT A TEMPERATURE NOT SUBSTANTIALLY EXCEEDING 40* C., AND RECOVERING THE RESULTING CRYSTALS OF ALKALI METAL PENICILLIN FROM THE RESULTING SATURATED SOLUTION THEREOF.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1955-07-01 | 1955-12-31 | 1956-07-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1959-07-01 | 1959-12-31 | 1960-07-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1963-07-01 | 1963-12-31 | 1964-07-01 | $7700.00 | Window Closed / Lapsed |